Attenuation of inflammatory bowel disease by oral administration of mucoadhesive polydopamine-coated yeast β-glucan via ROS scavenging and gut microbiota …
F Yang, Y Su, C Yan, T Chen, PCK Cheung - Journal of …, 2024 - Springer
Abstract Treatment for inflammatory bowel disease (IBD) is challenging since current anti-
inflammatory and immunosuppressive therapies do not address the underlying causes of …
inflammatory and immunosuppressive therapies do not address the underlying causes of …
Harnessing Immunomodulatory Polymers for Treatment of Autoimmunity, Allergy, and Transplant Rejection
AB Tu, G Krishna, KR Smith… - Annual Review of …, 2024 - annualreviews.org
Autoimmunity, allergy, and transplant rejection are a collection of chronic diseases that are
currently incurable, drastically decrease patient quality of life, and consume considerable …
currently incurable, drastically decrease patient quality of life, and consume considerable …
A synbiotic of Anaerostipes caccae and lactulose prevents and treats food allergy in mice
LA Hesser, AA Puente, J Arnold, E Ionescu, A Mirmira… - Cell Host & Microbe, 2024 - cell.com
Depletion of beneficial microbes by modern lifestyle factors correlates with the rising
prevalence of food allergies. Re-introduction of allergy-protective bacteria may be an …
prevalence of food allergies. Re-introduction of allergy-protective bacteria may be an …
Engineering nanoparticle therapeutics for food allergy
Food allergy is a growing public health issue among children and adults that can lead to life-
threatening anaphylaxis following allergen exposure. The criterion standard for disease …
threatening anaphylaxis following allergen exposure. The criterion standard for disease …
Novel strategies for modulating the gut microbiome for cancer therapy
Recent advancements in genomics, transcriptomics, and metabolomics have significantly
advanced our understanding of the human gut microbiome and its impact on the efficacy …
advanced our understanding of the human gut microbiome and its impact on the efficacy …
Alleviating Pyroptosis of Intestinal Epithelial Cells to Restore Mucosal Integrity in Ulcerative Colitis by Targeting Delivery of 4-Octyl-Itaconate
W Li, D Chen, Y Zhu, Q Ye, Y Hua, P Jiang, Y Xiang… - ACS Nano, 2024 - ACS Publications
Current therapies primarily targeting inflammation often fail to address the root relationship
between intestinal mucosal integrity and the resulting dysregulated cell death and ensuing …
between intestinal mucosal integrity and the resulting dysregulated cell death and ensuing …
Lonicera caerulea Pomace Alleviates DSS-Induced Colitis via Intestinal Barrier Improvement and Gut Microbiota Modulation
B Zhang, X Huang, L Niu, X Chen, B Hu, X Tang - Foods, 2023 - mdpi.com
The objective of this investigation was to appraise the mitigative effects of Lonicera caerulea
pomace (LCP)-supplemented diets on Dextran Sulfate Sodium (DSS)-induced colitis, and to …
pomace (LCP)-supplemented diets on Dextran Sulfate Sodium (DSS)-induced colitis, and to …
Injectable butyrate-prodrug micelles induce long-acting immune modulation and prevent autoimmune arthritis in mice
Short chain fatty acid (SCFAs), such as butyrate, have shown promising therapeutic potential
due to their immunomodulatory effects, particularly in maintaining immune homeostasis …
due to their immunomodulatory effects, particularly in maintaining immune homeostasis …
Integrated metabolomics and transcriptomics revealed the anti-constipation mechanisms of xylooligosaccharides from corn cobs
H Song, R Guo, X Sun, Y Kou, X Ma, Y Chen, L Song… - Food & Function, 2024 - pubs.rsc.org
Xylooligosaccharides (XOSs) have recently garnered interest for their potential as an anti-
constipation agent. In this study, we investigated the effects of XOSs derived from corn cobs …
constipation agent. In this study, we investigated the effects of XOSs derived from corn cobs …
Glycosylation-modified antigens as a tolerance-inducing vaccine platform prevent anaphylaxis in a pre-clinical model of food allergy
The only FDA-approved oral immunotherapy for a food allergy provides protection against
accidental exposure to peanuts. However, this therapy often causes discomfort or side …
accidental exposure to peanuts. However, this therapy often causes discomfort or side …