Alzheimer's disease (AD) and Parkinson's disease (PD) are devastating, frequent, and still
incurable neurodegenerative diseases that manifest as cognitive and motor disorders …

Objective Dementia has a multifactorial etiology, but the importance of individual health and
lifestyle related risk factors is often uncertain or based on few studies. The goal of this paper …

The brain has an extraordinary ability to functionally and physically change or reconfigure its
structure in response to environmental stimulus, cognitive demand, or behavioral …

For more than 50 years, psychologists, gerontologists, and, more recently, neuroscientists
have considered the possibility of successful aging. How to define successful aging remains …

No medications prevent or reverse age-related cognitive decline. Physical activity (PA)
enhances memory in rodents, but findings are mixed in human studies. As a result, exercise …

Yoga is the most popular complementary health approach practiced by adults in the United
States. It is an ancient mind and body practice with origins in Indian philosophy. Yoga …

The brain is the central organ for adaptation to experiences, including stressors, which are
capable of changing brain architecture as well as altering systemic function through …

Aerobic exercise improves cognitive and motor function by inducing neural changes
detected using molecular, cellular, and systems level neuroscience techniques. This review …

Background The mechanisms through which physical activity supports healthy brain function
remain to be elucidated. One hypothesis suggests that increased brain-derived neurotrophic …

Animal models point towards a key role of brain-derived neurotrophic factor (BDNF), insulin-
like growth factor-I (IGF-I) and vascular endothelial growth factor (VEGF) in mediating …