Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-
tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (M. tb), continues to be one of the
most prevalent infectious diseases in the world. There is an upward trend in occurrence due …

An important function of the gut microbiome is the fermentation of non-digestible dietary
fibers into short chain fatty acids (SCFAs). The three primary SCFAs: acetate, propionate …

Mucosal immunity consists of innate and adaptive immune responses which can be
influenced by systemic immunity. Despite having been the subject of intensive studies, it is …

Background. Histoplasmosis-associated hemophagocytic lymphohistiocytosis (HLH) is a
relatively rare disorder for which data are limited regarding optimal treatment and clinical …

Long-term changes in the immune system of successfully treated people living with HIV
(PLHIV) remain incompletely understood. In this study, we assessed 108 white blood cell …

In the setting of viral challenge, natural killer (NK) cells play an important role as an early
immune responder against infection. During this response, significant changes in the NK cell …

Background LAG-3 is a potent negative regulator of the immune response but its impact in
HIV infection in poorly understood. Unlike exhaustion markers such as PD-1, Tim-3, 2B4 and …

ABSTRACT Group 1 Innate Lymphoid Cells (which include Natural Killer cells and ILC1s)
aid in gut anti-bacterial defense through the production of IFNγ, which is critical for …

Bacterial sepsis is an important cause of morbidity and mortality in patients with HIV. HIV
causes increased susceptibility to invasive infections and affects sepsis pathogenesis …