Objective To review and appraise the validity and usefulness of published and preprint
reports of prediction models for prognosis of patients with covid-19, and for detecting people …

Abstract The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic
Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis …

Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …

Early recognition and treatment of sepsis are linked to improved patient outcomes. Machine
learning-based early warning systems may reduce the time to recognition, but few systems …

Background Coronavirus disease 2019 (COVID-19) can manifest as a viral-induced
hyperinflammation with multiorgan involvement. Such patients often experience rapid …

Importance Sepsis is a leading cause of death among children worldwide. Current pediatric-
specific criteria for sepsis were published in 2005 based on expert opinion. In 2016, the …

Background The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
on postoperative recovery needs to be understood to inform clinical decision making during …

Aims To compare demographic characteristics, clinical presentation, and outcomes of
patients with and without concomitant cardiac disease, hospitalized for COVID-19 in Brescia …

Respiratory failure in the acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
pandemic is hypothesized to be driven by an overreacting innate immune response, where …

Abstract The Sequential Organ Failure Assessment or SOFA score was developed to assess
the acute morbidity of critical illness at a population level and has been widely validated as a …