There is growing evidence of a strong association between the compromised autonomic
nervous system and sudden cardiac death. Heart rate variability (HRV) measures are widely …

Neurogenic pulmonary edema (NPE) is a life-threatening complication of central nervous
system (CNS) injuries. This review summarizes current knowledge about NPE etiology and …

The effects of continuous infusions of propofol on baroreceptor reflex regulation of cardiac
rate and peripheral sympathetic nerve activity were evaluated in seven healthy …

Background The use of propofol has been associated with episodes of bradycardias. The
mechanism (s) underlying these phenomena are not well defined. Therefore we investigated …

Objective To compare anaesthetic induction in healthy dogs using propofol or ketofol (a
propofol-ketamine mixture). Study design Prospective, randomized, controlled,'blinded'study …

Arterial baroreflex assessment using vasoactive substances enables investigators to collect
data pairs over a wide range of blood pressures and reflex reactions. These data pairs relate …

Background The effects of thoracic epidural anesthesia (TEA) on myocardial repolarization
and arrhythmogenicity are only incompletely understood. This is primarily because of the …

Interventions in the intensive care unit often require that the patient be sedated. Propofol is a
widely used, potent sedative agent that is popular in critical care and operating room …

In this study, we systematically examined the effects of ketamine and propofol at various
doses (5–20 mg/kg) on blood pressure, heart rate and renal sympathetic nerve activity in …

Background Although it is well recognized that anesthetics modulate the central control of
cardiorespiratory homeostasis, the cellular mechanisms by which anesthetics alter cardiac …