[HTML][HTML] Theoretical investigation and antineoplastic potential of Zn (II) and Pd (II) complexes of 6-methylpyridine-2-carbaldehyde-N (4)-ethylthiosemicarbazone
Abstract Density Functional Theoretical (DFT) and molecular docking studies have been
used to elucidate the antineoplastic potential of the ligand 6-Methylpyridine-2-carbaldehyde …
used to elucidate the antineoplastic potential of the ligand 6-Methylpyridine-2-carbaldehyde …
Glutathione: a key component of the cytoplasmic labile iron pool
RC Hider, XL Kong - Biometals, 2011 - Springer
The cytoplasmic labile iron pool supplies iron to the mitochondrion for heme and iron sulfur
cluster synthesis and to many cytoplasmic enzymes, thereby controlling numerous metabolic …
cluster synthesis and to many cytoplasmic enzymes, thereby controlling numerous metabolic …
Distinct mechanisms of ferritin delivery to lysosomes in iron-depleted and iron-replete cells
T Asano, M Komatsu, Y Yamaguchi-Iwai… - … and cellular biology, 2011 - Taylor & Francis
Ferritin is a cytosolic protein that stores excess iron, thereby protecting cells from iron
toxicity. Ferritin-stored iron is believed to be utilized when cells become iron deficient; …
toxicity. Ferritin-stored iron is believed to be utilized when cells become iron deficient; …
[HTML][HTML] Targeting cancer by binding iron: Dissecting cellular signaling pathways
GYL Lui, Z Kovacevic, V Richardson, AM Merlot… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Newer and more potent therapies are urgently needed to effectively treat advanced cancers
that have developed resistance and metastasized. One such strategy is to target cancer cell …
that have developed resistance and metastasized. One such strategy is to target cancer cell …
Iron metabolism and related genetic diseases: A cleared land, keeping mysteries
P Brissot, O Loréal - Journal of hepatology, 2016 - Elsevier
Body iron has a very close relationship with the liver. Physiologically, the liver synthesizes
transferrin, in charge of blood iron transport; ceruloplasmin, acting through its ferroxidase …
transferrin, in charge of blood iron transport; ceruloplasmin, acting through its ferroxidase …
No effects without causes: the Iron Dysregulation and Dormant Microbes hypothesis for chronic, inflammatory diseases
DB Kell, E Pretorius - Biological Reviews, 2018 - Wiley Online Library
Since the successful conquest of many acute, communicable (infectious) diseases through
the use of vaccines and antibiotics, the currently most prevalent diseases are chronic and …
the use of vaccines and antibiotics, the currently most prevalent diseases are chronic and …
Ferroptosis: biological rust of lipid membranes
B Hassannia, S Van Coillie… - Antioxidants & Redox …, 2021 - liebertpub.com
Significance: Iron is an essential element required for growth and proper functioning of the
body. However, an excess of labile ferrous iron increases the risk of oxidative stress-induced …
body. However, an excess of labile ferrous iron increases the risk of oxidative stress-induced …
Recent trends in metal ion based hydrogel biomaterials for tissue engineering and other biomedical applications
G Janarthanan, I Noh - Journal of Materials Science & Technology, 2021 - Elsevier
Recently, the metal ion cross-linked hydrogels have gained enormous interest because of its
excellent properties like self-healing, fast recovery, biocompatibility and high mechanical …
excellent properties like self-healing, fast recovery, biocompatibility and high mechanical …
Metallobiology of Lactobacillaceae in the gut microbiome
U Huynh, ML Zastrow - Journal of inorganic biochemistry, 2023 - Elsevier
Lactobacillaceae are a diverse family of lactic acid bacteria found in the gut microbiota of
humans and many animals. These bacteria exhibit beneficial effects on intestinal health …
humans and many animals. These bacteria exhibit beneficial effects on intestinal health …
Molecular mechanisms of ferroptosis and its role in pulmonary disease
N Tao, K Li, J Liu - Oxidative Medicine and Cellular Longevity, 2020 - Wiley Online Library
Ferroptosis is a new mode of cell death that is characterized by the excessive accumulation
of iron and lipid peroxides. It has unique morphological changes and disparate biochemical …
of iron and lipid peroxides. It has unique morphological changes and disparate biochemical …