Speciation in human blood of Metvan, a vanadium based potential anti-tumor drug

D Sanna, V Ugone, G Micera, P Buglyó, L Bíró… - Dalton …, 2017 - pubs.rsc.org
The first report on the anti-cancer activity of the compound Metvan,[VIVO (Me2phen) 2
(SO4)], where Me2phen is 4, 7-dimethyl-1, 10-phenanthroline, dates back to 2001. Although …

Deciphering the iron response in Acinetobacter baumannii: a proteomics approach

CC Nwugo, JA Gaddy, DL Zimbler, LA Actis - Journal of proteomics, 2011 - Elsevier
Iron is an essential nutrient that plays a role in bacterial differential gene expression and
protein production. Accordingly, the comparative analysis of total lysate and outer …

Binding of α-synuclein with Fe (III) and with Fe (II) and biological implications of the resultant complexes

Y Peng, C Wang, HH Xu, YN Liu, F Zhou - Journal of inorganic biochemistry, 2010 - Elsevier
Parkinson's disease (PD) is hallmarked by the abnormal intracellular inclusions (Lewy
bodies or LBs) in dopaminergic cells. Amyloidogenic protein α-synuclein (α-syn) and iron …

[HTML][HTML] Iron status and its relations with oxidative damage and bone loss during long-duration space flight on the International Space Station

SR Zwart, JLL Morgan, SM Smith - The American journal of clinical nutrition, 2013 - Elsevier
Background: Increases in stored iron and dietary intake of iron during space flight have
raised concern about the risk of excess iron and oxidative damage, particularly in bone …

[HTML][HTML] The Acinetobacter baumannii entA Gene Located Outside the Acinetobactin Cluster Is Critical for Siderophore Production, Iron Acquisition and Virulence

WF Penwell, BA Arivett, LA Actis - PloS one, 2012 - journals.plos.org
Acinetobacter baumannii causes severe infections in compromised patients, who present an
iron-limited environment that controls bacterial growth. This pathogen has responded to this …

[HTML][HTML] The Mycobacterium tuberculosis secreted protein Rv0203 transfers heme to membrane proteins MmpL3 and MmpL11

CP Owens, N Chim, AB Graves, CA Harmston… - Journal of Biological …, 2013 - ASBMB
Mycobacterium tuberculosis is the causative agent of tuberculosis, which is becoming an
increasingly global public health problem due to the rise of drug-resistant strains. While …

Iron availability and homeostasis in plants: a review of responses, adaptive mechanisms, and signaling

N Kermeur, M Pédrot, F Cabello-Hurtado - Plant Abiotic Stress Signaling, 2023 - Springer
Iron is an essential element for all living organisms, playing a major role in plant
biochemistry as a redox catalyst based on iron redox properties. Iron is the fourth most …

Recent advancements in nanomaterial-mediated ferroptosis-induced cancer therapy: Importance of molecular dynamics and novel strategies

N Dhas, R Kudarha, R Tiwari, G Tiwari, N Garg… - Life Sciences, 2024 - Elsevier
Ferroptosis is a novel type of controlled cell death resulting from an imbalance between
oxidative harm and protective mechanisms, demonstrating significant potential in combating …

ESI-MS study of the interaction of potential oxidovanadium (IV) drugs and amavadin with model proteins

V Ugone, D Sanna, G Sciortino, DC Crans… - Inorganic …, 2020 - ACS Publications
In this study, the binding to lysozyme (Lyz) of four important VIV compounds with antidiabetic
and/or anticancer activity,[VIVO (pic) 2 (H2O)],[VIVO (ma) 2],[VIVO (dhp) 2], and [VIVO (acac) …

Physico-chemical properties of the new generation IV iron preparations ferumoxytol, iron isomaltoside 1000 and ferric carboxymaltose

S Neiser, D Rentsch, U Dippon, A Kappler, PG Weidler… - Biometals, 2015 - Springer
The advantage of the new generation IV iron preparations ferric carboxymaltose (FCM),
ferumoxytol (FMX), and iron isomaltoside 1000 (IIM) is that they can be administered in …