Smokeless tobacco and cancer

P Boffetta, S Hecht, N Gray, P Gupta, K Straif - The lancet oncology, 2008 - thelancet.com
Use of smokeless tobacco products is common worldwide, with increasing consumption in
many countries. Although epidemiological data from the USA and Asia show a raised risk of …

Mechanisms of toxicity and biomarkers of flavoring and flavor enhancing chemicals in emerging tobacco and non-tobacco products

G Kaur, T Muthumalage, I Rahman - Toxicology letters, 2018 - Elsevier
Tobacco products containing flavorings, such as electronic nicotine delivery devices (ENDS)
or e-cigarettes, cigars/cigarillos, waterpipes, and heat-not-burn devices (iQOS) are …

[HTML][HTML] Metabolism and DNA Adduct Formation of Tobacco-Specific N-Nitrosamines

Y Li, SS Hecht - International journal of molecular sciences, 2022 - mdpi.com
The tobacco-specific N-nitrosamines 4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone
(NNK) and N′-nitrosonornicotine (NNN) always occur together and exclusively in tobacco …

Reduced nicotine content cigarettes: effects on toxicant exposure, dependence and cessation

DK Hatsukami, M Kotlyar, LA Hertsgaard, Y Zhang… - …, 2010 - Wiley Online Library
Aims To examine the effects of reduced nicotine cigarettes on smoking behavior, toxicant
exposure, dependence and abstinence. Design Randomized, parallel arm, semi‐blinded …

Biomarkers of tobacco exposure: summary of an FDA-sponsored public workshop

CM Chang, SH Edwards, A Arab… - … Biomarkers & Prevention, 2017 - AACR
Since 2009, the FDA Center for Tobacco Products (CTP) has had the authority to regulate
the manufacturing, distribution, and marketing of tobacco products in order to reduce the …

Exposure and metabolic activation biomarkers of carcinogenic tobacco-specific nitrosamines

SS Hecht, I Stepanov, SG Carmella - Accounts of chemical …, 2016 - ACS Publications
Conspectus Lung cancer is the leading cause of cancer death in the world, and cigarette
smoking is its main cause. Oral cavity cancer is another debilitating and often fatal cancer …

[图书][B] Smokeless tobacco and some tobacco-specific N-nitrosamines

IARC Working Group on the Evaluation of … - 2007 - books.google.com
This eighty-ninth volume of the IARC Monographs is the third and last of a series on tobacco-
related agents. Volume 83 reported on the carcinogenicity of tobacco smoke and involuntary …

Presence of the Carcinogen N′-Nitrosonornicotine in Saliva of E-cigarette Users

G Bustamante, B Ma, G Yakovlev… - Chemical research in …, 2018 - ACS Publications
Many harmful constituents are present in e-cigarettes at much lower levels than in cigarette
smoke, and the results of analysis of urinary biomarkers in e-cigarette users are consistent …

[HTML][HTML] Development of estimates of dietary nitrates, nitrites, and nitrosamines for use with the Short Willet Food Frequency Questionnaire

JS Griesenbeck, MD Steck, JC Huber, JR Sharkey… - Nutrition journal, 2009 - Springer
Background Studies have suggested that nitrates, nitrites, and nitrosamines have an
etiologic role in adverse pregnancy outcomes and chronic diseases such as cancer …

[HTML][HTML] Smoking and reproduction: the oviduct as a target of cigarette smoke

P Talbot, K Riveles - Reproductive Biology and Endocrinology, 2005 - Springer
The oviduct is an exquisitely designed organ that functions in picking-up ovulated oocytes,
transporting gametes in opposite directions to the site of fertilization, providing a suitable …