Abstract TIP GROWTH DEFECTIVE1 (TIP1) of Arabidopsis thaliana affects cell growth
throughout the plant and has a particularly strong effect on root hair growth. We have …

Abstract Huntingtin interacting protein 14 (HIP14, ZDHHC17) is a huntingtin (HTT)
interacting protein with palmitoyl transferase activity. In order to interrogate the function of …

The heterotrimeric G protein α subunit (Gα) is targeted to the cytoplasmic face of the plasma
membrane through reversible lipid palmitoylation and relays signals from G-protein-coupled …

Protein palmitoylation plays an important role in the structure and function of a wide array of
proteins. Unlike other lipid modifications, protein palmitoylation is highly dynamic and cycles …

Protein palmitoylation is a widespread lipid modification in which one or more cysteine thiols
on a substrate protein are modified to form a thioester with a palmitoyl group. This lipid …

Palmitoylation plays important roles in the regulation of protein localization, stability, and
activity. The protein acyltransferases (PATs) have a common DHHC Cys-rich domain …

Cysteine-string protein (CSP) is an extensively palmitoylated DnaJ-family chaperone, which
exerts an important neuroprotective function. Palmitoylation is required for the intracellular …

Huntington's disease (HD) is an autosomal dominant, late onset, neurodegenerative
disease characterized by motor deficits and dementia that is caused by expansion of a CAG …

X-linked mental retardation (XLMR) affects one in 600 males and is highly heterogeneous.
We describe here a 29-year-old woman with severe nonsyndromic mental retardation and a …

Protein S-palmitoylation, the most common lipid modification with the 16-carbon fatty acid
palmitate, provides an important mechanism for regulating protein trafficking and function …