Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is
essential for cell division and can inhibit cell death. Normally it is only expressed in actively …

Survivin is the smallest member of the Inhibitor of apoptosis (IAP) family of proteins, involved
in inhibition of apoptosis and regulation of cell cycle. These functional attributes make …

Survivin, as a member of the inhibitor of apoptosis proteins (IAPs) family, acts as a
suppressor of apoptosis and plays a central role in cell division. Survivin has been …

Survivin is one of the rare proteins that is differentially expressed in normal and cancer cells
and is directly or indirectly involved in numerous pathways required for tumor maintenance …

Although technically a member of the Inhibitor of Apoptosis (IAP) gene family, survivin has
consistently defied assumptions, refuted predictions and challenged paradigms. Despite its …

Aurora kinase A (AURKA) has been implicated in the regulation of cell cycle progression,
mitosis and a key number of oncogenic signaling pathways in various malignancies …

Survivin is a protein functionally important for cell division, apoptosis, and possibly, for micro-
RNA biogenesis. It is an established marker of malignant cell transformation. In non …

The small GTPase KRAS is frequently mutated in pancreatic cancer and its cooperation with
the transcription factor MYC is essential for malignant transformation. The key to oncogenic …

Survivin (BIRC5) is a tumor-associated antigen (TAA) overexpressed in various tumors but
present at low to undetectable levels in normal tissue. Survivin is known to have a high …

The etiology of endometriosis is highly complex, and although it is a benign disease, it has
several biological behaviors similar to malignant lesions, including cell invasion, neo …