Toll-like receptor-guided therapeutic intervention of human cancers: molecular and immunological perspectives

S Mukherjee, R Patra, P Behzadi, A Masotti… - Frontiers in …, 2023 - frontiersin.org
Toll-like receptors (TLRs) serve as the body's first line of defense, recognizing both
pathogen-expressed molecules and host-derived molecules released from damaged or …

[HTML][HTML] Serine protease inhibitor from the muscle larval Trichinella spiralis ameliorates non-alcoholic fatty liver disease in mice via anti-inflammatory properties and …

M Tong, X Yang, Y Qiao, G Liu, H Ge, G Huang… - Biomedicine & …, 2024 - Elsevier
Trichinella spiralis is recognized for its ability to regulate host immune responses. The serine
protease inhibitor of T. spiralis (Ts-SPI) participates in T. spiralis-mediated …

Immune targeting of filarial glutaredoxin through a multi-epitope peptide-based vaccine: A reverse vaccinology approach

NC Das, S Gorai, PSS Gupta, SK Panda… - International …, 2024 - Elsevier
Despite the efforts of global programme to eliminate lymphatic filariasis (GPELF), the threat
of lymphatic filariasis (LF) still looms over humanity in terms of long-term disabilities, and …

Deciphering the pH-dependent oligomerization of aspartate semialdehyde dehydrogenase from Wolbachia endosymbiont of Brugia malayi: An in vitro and in silico …

A Mathimaran, H Nagarajan, A Mathimaran… - International Journal of …, 2024 - Elsevier
The enzyme aspartate semialdehyde dehydrogenase (ASDH) plays a pivotal role in the
amino acid biosynthesis pathway, making it an attractive target for the development of new …

[HTML][HTML] Schistosoma japonicum cystatin alleviates paraquat poisoning caused acute lung injury in mice through activating regulatory macrophages

Y Wu, H Gao, H Yu, X Wang, H Li, Q Jin, X Zhu… - Ecotoxicology and …, 2024 - Elsevier
Background Paraquat (PQ) is a widely used herbicide that poisons human by accident or
intentional ingestion. PQ poisoning causes systemic inflammatory response syndrome …

Helminth-derived biomolecules as potential therapeutics against ulcerative colitis

A Chakraborty, J Bayry, S Mukherjee - Immunotherapy, 2024 - Taylor & Francis
'Helminth therapy'has been in the limelight over the last two decades. Extensive research
has unveiled the tendency of helminth and helminth derivatives to interact with various arms …

Genetic makeup of Trichuris hominibus, a novel Trichuris species naturally infecting humans and displaying signs of resistance to drug treatment

MA Bär, NA Kouamé, S Touré, JT Coulibaly… - bioRxiv, 2024 - biorxiv.org
Trichuriasis is a neglected tropical disease that affects as many as 500 million individuals
and can cause significant morbidity, even death. For decades, it is thought to be caused by …

[HTML][HTML] Using Helminths to Fight Cancer: An Innovative Approach

N Ameli, A Masoumi, M Kerachi… - World's Veterinary …, 2023 - cyberleninka.ru
As an alternative treatment in cancer therapy, there has been a growing interest in using
helminths, such as Trichinella spiralis (T. spiralis), Echinococcus granulosus (E …

[PDF][PDF] Corpus Journal of Dairy and Veterinary Science (CJDVS)

DA Pollard - corpuspublishers.com
Abstract Autoimmune disorders like Multiple Sclerosis (MS), rheumatoid arthritis, and
inflammatory bowel disease occur when your body's mounts a response to itself. Genetic …