Epigenetics is the study of heritable changes in gene expression that do not involve
changes to the underlying DNA sequence. It is a change in phenotype without changing in …

The skeletal muscle represents up to 40% of the human body mass and plays an important
role not only for locomotion, but also as a regulator of whole body metabolism and as an …

[eng] HDAC11 is the newest member of the histone deacetylase (HDAC) family and one of
the less studied. Its expression was described to be enriched in skeletal muscle tissues from …

Skeletal muscle facilitates movement through contraction, which requires substantial energy
production. Therefore, proper metabolism is essential for muscle homeostasis. Interestingly …

DNA is the physical medium for information storage inside of cells. Sub-regions of the DNA
composed of linear stretches of nucleic acid sequences (DNA sequences), known as genes …

Alternative pre-mRNA splicing in higher eukaryotes enhances transcriptome complexity and
proteome diversity. Its regulation is mediated by a complex RNA-protein network that is …

Cell differentiation is the foundation for tissue development and regeneration, disease
modeling, and cell-based therapies. The differentiation of skeletal myoblasts has been well …

Цель данного обзора является обратить внимание на некоторые достижений в
изучении рабдомиосаркомы у детей. На основании недавних результатов …

Embryonal Rhabdomyosarcoma (RMS) is a pediatric soft-tissue sarcoma derived from
myogenic precursors that is characterized by a good prognosis in patients with localized …

Myogenic differentiation is a critical and highly regulated process that occurs during
embryogenesis. Many studies have investigated the role of Muscle Regulatory Factor (MRF) …