Daphnetin (DAP), a coumarin derivative extracted from Daphne species, is biologically
active phytochemical with copious bioactivities including anti-inflammatory, anti-oxidant …

Skeletal muscle, which accounts for approximately 40% of total body weight, is one of the
most dynamic and plastic tissues in the human body and plays a vital role in movement …

Background and purpose Evidence indicates that ferroptosis plays a key role in acute kidney
injury induced by cisplatin. The Nrf2/NRF2 pathway regulates oxidative stress, lipid …

Oxidative damage can lead to severe ovarian dysfunctions and even premature ovarian
failure. Nrf2, a significant transcription factor that regulates the oxidative stress response of …

Epidemiologic studies have shown that fine particulate matter 2.5 (PM2. 5) exaggerates
airway inflammation associated with acute exacerbation of chronic obstructive pulmonary …

In the treatment of malignant tumors, the effectiveness of cisplatin (CP) is limited by its
nephrotoxicity, leading to cisplatin‐induced acute kidney injury (CP‐AKI). Polydatin (PD) has …

Abstract Aristolochic acid I (AA-I), presenting in a variety of natural medicinal plants, which
could cause tubular epithelial cell injury. Curcumin (CUR), a polyphenolic substance …

Drug-induced liver and kidney damage is an emergent clinical issue that should be
addressed. Rosmarinic acid (RA) has obvious anti-inflammatory and antioxidant effects, so …

Purpose Testicular toxicity is one of the most important side effects of cisplatin (CP) therapy.
Alpha-pinene (AP) is a naturally occurring monoterpene with antioxidant character in plants …

Cisplatin (DDP), a widely used chemotherapeutic drug in cancer treatment, causes oxidative
stress, resulting in cancer cachexia and skeletal muscle atrophy. This study investigated the …