Non-infectious uveitis (NIU) refers to various intraocular inflammatory disorders responsible
for severe visual loss. Cytokines participate in the regulation of ocular homeostasis and NIU …

Purpose. To evaluate the effectiveness of Janus kinase (JAK) inhibitors for the treatment of
patients with autoimmune disease and associated inflammatory ocular diseases. Methods …

Autoimmune uveitis is a non-infectious intraocular condition that affects the uveal tract of the
eye and threatens vision if not treated properly. Increasing evidence suggests that activated …

Juvenile idiopathic arthritis (JIA) is the most common extraocular disease associated with
pediatric uveitis. Despite the growing knowledge about the pathogenetic and clinical …

Behçet's disease is a rare and poorly understood vasculitis affecting blood vessels of all
types and sizes. Uveitis and oral and genital ulcers represent the typical clinical triad …

Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis
(UC), are lifelong diseases characterized by chronic inflammation of the gastrointestinal tract …

Objective Anterior uveitis is a common extra‐articular manifestation of axial spondyloarthritis
(AxSpA). We set to evaluate the risk of anterior uveitis (AU) with biologics and synthetic …

We have previously reported that inhibition of the Janus kinase 1 (JAK1) signaling
ameliorates IL-17A-mediated blood-retinal barrier (BRB) dysfunction. Higher levels of IL-17A …

Purpose Inflammation is involved in the pathogenesis of diabetes, however the impact of
diabetes on organ-specific autoimmune diseases remains unexplored. Experimental …

Ocular disease, such as scleritis and peripheral ulcerative keratitis (PUK), may be a serious
ocular complication. We present a patient with severe and refractory PUK treated with …