The roles of cellular reactive oxygen species, oxidative stress and antioxidants in pregnancy outcomes

KH Al-Gubory, PA Fowler, C Garrel - … journal of biochemistry & cell biology, 2010 - Elsevier
Reactive oxygen species (ROS) are generated as by-products of aerobic respiration and
metabolism. Mammalian cells have evolved a variety of enzymatic mechanisms to control …

Oxidative stress and protection against reactive oxygen species in the pre-implantation embryo and its surroundings

P Guerin, S El Mouatassim… - Human reproduction …, 2001 - academic.oup.com
Oxidative stress is involved in the aetiology of defective embryo development. Reactive
oxygen species (ROS) may originate from embryo metabolism and/or embryo surroundings …

Large offspring syndrome in cattle and sheep.

LE Young, KD Sinclair, I Wilmut - Reviews of reproduction, 1998 - europepmc.org
Bovine and ovine embryos exposed to a variety of unusual environments prior to the
blastocyst stage have resulted in the development of unusually large offspring which can …

The role of antioxidant enzymes in the ovaries

S Wang, G He, M Chen, T Zuo, W Xu… - Oxidative medicine and …, 2017 - Wiley Online Library
Proper physiological function of the ovaries is very important for the entire female
reproductive system and overall health. Reactive oxygen species (ROS) are generated as …

Bovine embryo culture in the presence or absence of serum: implications for blastocyst development, cryotolerance, and messenger RNA expression

D Rizos, A Gutiérrez-Adán… - Biology of …, 2003 - academic.oup.com
We have previously shown that, while the intrinsic quality of the oocyte is the main factor
affecting blastocyst yield during bovine embryo development in vitro, the main factor …

Could oxidative stress influence the in-vitro maturation of oocytes?

CMH Combelles, S Gupta, A Agarwal - Reproductive biomedicine online, 2009 - Elsevier
In the efforts aimed at improving the quality of in-vitro-matured human oocytes, the dynamic
balance and roles of pro-/antioxidants merit further consideration. In-vitromaturation (IVM) is …

Cellular and molecular deviations in bovine in vitro-produced embryos are related to the large offspring syndrome

G Lazzari, C Wrenzycki, D Herrmann… - Biology of …, 2002 - academic.oup.com
The large offspring syndrome (LOS) is observed in bovine and ovine offspring following
transfer of in vitro-produced (IVP) or cloned embryos and is characterized by a multitude of …

Alterations of expression of developmentally important genes in preimplantation bovine embryos by in vitro culture conditions: implications for subsequent …

H Niemann, C Wrenzycki - Theriogenology, 2000 - Elsevier
Recent advances in molecular technology and in vitro production of bovine embryos have
enabled studies of gene transcription in preimplantation embryos. On the basis of …

Animal oocyte and embryo cryopreservation

RM Pereira, CC Marques - Cell and tissue banking, 2008 - Springer
Cryopreservation of oocytes and embryos is a crucial step for the widespread and
conservation of animal genetic resources. However, oocytes and early embryos are very …

Expression of genes encoding antioxidant enzymes in human and mouse oocytes during the final stages of maturation

S El Mouatassim, P Guerin… - Molecular human …, 1999 - academic.oup.com
The mRNA expression of five enzymes: catalase, Cu-Zn-superoxide dismutase (Cu-Zn-
SOD), Mn-superoxide dismutase (Mn-SOD), glutathione peroxidase (GPX), and γ …