Insights into the Evolving Epidemiology of Clostridioides difficile Infection and Treatment: A Global Perspective

C Liu, T Monaghan, A Yadegar, T Louie, D Kao - Antibiotics, 2023 - mdpi.com
Clostridioides difficile remains an important public health threat, globally. Since the
emergence of the hypervirulent strain, ribotype 027, new strains have been reported to …

Clostridioides (Clostridium) difficile infection in hospitalized patients with antibiotic-associated diarrhea: A systematic review and meta-analysis

MJ Nasiri, M Goudarzi, B Hajikhani, M Ghazi… - Anaerobe, 2018 - Elsevier
Clostridium difficile is the main infectious cause of antibiotic associated diarrhea (AAD). The
objective of this study was to determine the frequency of C. difficile AAD in hospitalized …

The incidence and drug resistance of Clostridium difficile infection in Mainland China: a systematic review and meta-analysis

C Tang, L Cui, Y Xu, L Xie, P Sun, C Liu, W Xia… - Scientific reports, 2016 - nature.com
It has been widely reported that the incidence and severity of Clostridium difficile infection
(CDI) have increased dramatically in North America and Europe. However, little is known …

Status of vaccine research and development for Clostridium difficile

TV Riley, D Lyras, GR Douce - Vaccine, 2019 - Elsevier
Clostridium difficile associated disease is fundamentally associated with dysbiosis of the gut
microbiome as a consequence of antibiotic use. This is because this sporulating, obligate …

Assessing the burden of Clostridium difficile infection in low-and middle-income countries

GA Roldan, AX Cui, NR Pollock - Journal of clinical microbiology, 2018 - Am Soc Microbiol
In contrast to the significant resources invested in the diagnosis and prevention of
Clostridium difficile infection (CDI) in resource-rich settings, in resource-limited settings …

[HTML][HTML] Prevalence and molecular epidemiology of Clostridium difficile infection in Thailand

P Putsathit, M Maneerattanaporn, P Piewngam… - New Microbes and New …, 2017 - Elsevier
Little is known about Clostridium difficile infection (CDI) in Asia generally, and specifically in
Thailand. Given the high prevalence of inappropriate antibiotic usage in this region, CDI is …

Clostridium difficile infection: early history, diagnosis and molecular strain typing methods

C Rodriguez, J Van Broeck, B Taminiau, M Delmée… - Microbial …, 2016 - Elsevier
Recognised as the leading cause of nosocomial antibiotic-associated diarrhoea, the
incidence of Clostridium difficile infection (CDI) remains high despite efforts to improve …

Clostridium difficile in Asia: Opportunities for One Health Management

DA Collins, TV Riley - Tropical Medicine and Infectious Disease, 2018 - mdpi.com
Clostridium difficile is a ubiquitous spore-forming bacterium which causes toxin-mediated
diarrhoea and colitis in people whose gut microflora has been depleted by antimicrobial …

[HTML][HTML] Disease burden of Clostridium difficile infections in adults, Hong Kong, China, 2006–2014

J Ho, RZW Dai, TNY Kwong, X Wang… - Emerging infectious …, 2017 - ncbi.nlm.nih.gov
Cross-sectional studies suggest an increasing trend in incidence and relatively low
recurrence rates of Clostridium difficile infections in Asia than in Europe and North America …

High prevalence and diversity of tcdA-negative and tcdB-positive, and non-toxigenic, Clostridium difficile in Thailand

K Imwattana, P Wangroongsarb, TV Riley - Anaerobe, 2019 - Elsevier
Studies on the prevalence and diversity of Clostridium difficile in Thailand have been limited
to those derived from a few tertiary hospitals in Central Thailand. In this study, 145 C. difficile …