The versatile type IV secretion system (T4SS) nanomachine plays a pivotal role in bacterial
pathogenesis and the propagation of antibiotic resistance determinants throughout microbial …

Confusion about strain classification and nomenclature permeates modern microbiology.
Although taxonomists have traditionally acted as gatekeepers of order, the numbers of, and …

Many bacterial genomes are highly variable but nonetheless are typically published as a
single assembled genome. Experiments tracking bacterial genome evolution have not …

Background Helicobacter pylori infection that is usually acquired in childhood and lasts for
lifetime is mostly asymptomatic but associated with severe gastrointestinal disease including …

Microbial species diversify into strains through single-nucleotide mutations and structural
changes, such as recombination, insertions and deletions. Most strain-comparison methods …

The immune microenvironment plays a critical regulatory role in the pathogenesis of
Helicobacter pylori (H. pylori). Understanding the mechanisms that drive the transition from …

Background Genomes are subjected to rearrangements that change the orientation and
ordering of genes during evolution. The most common rearrangements that occur in uni …

Isolates of Helicobacter pylori can be classified phylogeographically. High genetic diversity
and rapid microevolution are a hallmark of H. pylori genomes, a phenomenon that is …

Aims The aim of this work was to investigate the interaction between two Helicobacter pylori
strains in promoting genetic transfer, when grown in the biofilm mode. Methods and Results …

Helicobacter pylori is a Gram-negative ε-proteobacterium that colonizes about 50% of
humans. Some pertinent characteristics are that it can survive the acid of the stomach …