Sorting through the extensive and confusing roles of sortilin in metabolic disease
Sortilin is a post-Golgi trafficking receptor homologous to the yeast vacuolar protein sorting
receptor 10 (VPS10). The VPS10 motif on sortilin is a 10-bladed β-propeller structure …
receptor 10 (VPS10). The VPS10 motif on sortilin is a 10-bladed β-propeller structure …
Deficiency of PSRC1 accelerates atherosclerosis by increasing TMAO production via manipulating gut microbiota and flavin monooxygenase 3
T Luo, Z Guo, D Liu, Z Guo, Q Wu, Q Li, R Lin… - Gut …, 2022 - Taylor & Francis
Maladaptive inflammatory and immune responses are responsible for intestinal barrier
integrity and function dysregulation. Proline/serine-rich coiled-coil protein 1 (PSRC1) …
integrity and function dysregulation. Proline/serine-rich coiled-coil protein 1 (PSRC1) …
Genetic, lifestyle and metabolic factors contributing to cardiovascular disease in the Italian population: a literature review
C Ojeda-Granados, E Campisi, M Barchitta… - Frontiers in …, 2024 - frontiersin.org
Cardiovascular diseases (CVD) represent a major health problem worldwide. In Italy,
despite the decline in CVD mortality and disability-adjusted life years recently observed …
despite the decline in CVD mortality and disability-adjusted life years recently observed …
Powerful and robust inference of complex phenotypes' causal genes with dependent expression quantitative loci by a median-based Mendelian randomization
Isolating the causal genes from numerous genetic association signals in genome-wide
association studies (GWASs) of complex phenotypes remains an open and challenging …
association studies (GWASs) of complex phenotypes remains an open and challenging …
Genetic variations of low-density lipoprotein cholesterol on metabolic disorders in obstructive sleep apnea
Y Peng, H Shen, C Li, X Zhu, Y Gao, H Yi, H Xu… - Nutrition & …, 2024 - Springer
Background The study aimed to explore the relationship between low-density lipoprotein
cholesterol (LDL-C) genetic variants and obstructive sleep apnea (OSA) and its …
cholesterol (LDL-C) genetic variants and obstructive sleep apnea (OSA) and its …
Deficiency of proline/serine-rich coiled-coil protein 1 (PSRC1) accelerates trimethylamine N-oxide-induced atherosclerosis in ApoE−/− mice
T Luo, D Liu, Z Guo, P Chen, Z Guo, C Ou… - Journal of Molecular and …, 2022 - Elsevier
Aims The main therapeutic strategies for coronary artery disease (CAD) are mainly based on
the correction of abnormal cholesterol levels; however, residual risks remain. The newly …
the correction of abnormal cholesterol levels; however, residual risks remain. The newly …
[HTML][HTML] Association of CELSR2, APOB100, ABCG5/8, LDLR, and APOE polymorphisms and their genetic risks with lipids among the Thai subjects
M Nuinoon, W Saiphak, N Nawaka… - Saudi Journal of …, 2023 - Elsevier
Background Hypercholesterolemia is a common cardiovascular risk factor. The aim of this
study was to investigate the association of CELSR2 (rs629301), APOB100 (rs1367117) …
study was to investigate the association of CELSR2 (rs629301), APOB100 (rs1367117) …
[PDF][PDF] Genetic Risks of Cardiovascular Diseases
W Angkatavanich - academia.edu
Coronary Heart Disease (CHD) is the number one cause of death in the current world. Since
numerous reasons heighten the risk of CHD, this review will focus only on genetic risk …
numerous reasons heighten the risk of CHD, this review will focus only on genetic risk …