IBD disease-modifying therapies: insights from emerging therapeutics
Inflammatory bowel disease (IBD) pathogenesis is associated with gut mucosal
inflammation, epithelial damage, and dysbiosis leading to a dysregulated gut mucosal …
inflammation, epithelial damage, and dysbiosis leading to a dysregulated gut mucosal …
[HTML][HTML] Role of antibiotics for treatment of inflammatory bowel disease
O Nitzan, M Elias, A Peretz, W Saliba - World journal of …, 2016 - ncbi.nlm.nih.gov
Inflammatory bowel disease is thought to be caused by an aberrant immune response to gut
bacteria in a genetically susceptible host. The gut microbiota plays an important role in the …
bacteria in a genetically susceptible host. The gut microbiota plays an important role in the …
Lactobacillus accelerates ISCs regeneration to protect the integrity of intestinal mucosa through activation of STAT3 signaling pathway induced by LPLs secretion of …
Q Hou, L Ye, H Liu, L Huang, Q Yang… - Cell Death & …, 2018 - nature.com
The regeneration of intestinal epithelial are maintained by continuous differentiation and
proliferation of intestinal stem cells (ISCs) under physiological and pathological conditions …
proliferation of intestinal stem cells (ISCs) under physiological and pathological conditions …
Stress triggers flare of inflammatory bowel disease in children and adults
Y Sun, L Li, R Xie, B Wang, K Jiang, H Cao - Frontiers in pediatrics, 2019 - frontiersin.org
Inflammatory bowel disease (IBD) is an idiopathic inflammatory disease characterized by
chronic and relapsing manifestations. It is noteworthy that the prevalence of IBD is gradually …
chronic and relapsing manifestations. It is noteworthy that the prevalence of IBD is gradually …
[HTML][HTML] Evidence for interplay among antibacterial-induced gut microbiota disturbance, neuro-inflammation, and anxiety in mice
HM Jang, HJ Lee, SE Jang, MJ Han, DH Kim - Mucosal immunology, 2018 - Elsevier
The aim of the present study was to determine whether there is the mechanistic connection
between antibacterial-dependent gut microbiota disturbance and anxiety. First, exposure of …
between antibacterial-dependent gut microbiota disturbance and anxiety. First, exposure of …
How the microbiota shapes rheumatic diseases
T Van de Wiele, JT Van Praet, M Marzorati… - Nature Reviews …, 2016 - nature.com
The human gut harbours a tremendously diverse and abundant microbial community that
correlates with, and even modulates, many health-related processes. The mucosal …
correlates with, and even modulates, many health-related processes. The mucosal …
Adherent-Invasive E. coli: Update on the Lifestyle of a Troublemaker in Crohn's Disease
M Chervy, N Barnich, J Denizot - International Journal of Molecular …, 2020 - mdpi.com
Besides genetic polymorphisms and environmental factors, the intestinal microbiota is an
important factor in the etiology of Crohn's disease (CD). Among microbiota alterations, a …
important factor in the etiology of Crohn's disease (CD). Among microbiota alterations, a …
[HTML][HTML] Polyphenols from food by-products: An alternative or complementary therapy to IBD conventional treatments
AP da Fonseca Machado, MV Geraldi… - Food research …, 2021 - Elsevier
Inflammatory bowel diseases (IBD) are illnesses characterized by chronic intestinal
inflammation and microbial dysbiosis that have emerged as a public health challenge …
inflammation and microbial dysbiosis that have emerged as a public health challenge …
Xenobiotics: interaction with the intestinal microflora
K Lu, R Mahbub, JG Fox - ILAR journal, 2015 - academic.oup.com
The human body is host to 100 trillion gut microbes, approximately 10-times more than all
human cells. It is estimated that the approximately 500–1000 species residing in the human …
human cells. It is estimated that the approximately 500–1000 species residing in the human …
Gut microbiota‐stem cell niche crosstalk: A new territory for maintaining intestinal homeostasis
Intestinal epithelium undergoes rapid cellular turnover, relying on the local niche, to support
intestinal stem cells (ISCs) function and self‐renewal. Research into the association …
intestinal stem cells (ISCs) function and self‐renewal. Research into the association …