Vulvovaginal candidiasis: Epidemiology, microbiology and risk factors

B Gonçalves, C Ferreira, CT Alves… - Critical reviews in …, 2016 - Taylor & Francis
Vulvovaginal candidiasis (VVC) is an infection caused by Candida species that affects
millions of women every year. Although Candida albicans is the main cause of VVC, the …

Synthetic nanoparticles for vaccines and immunotherapy

DJ Irvine, MC Hanson, K Rakhra, T Tokatlian - Chemical reviews, 2015 - ACS Publications
The immune system plays a critical role in our health. No other component of human
physiology plays a decisive role in as diverse an array of maladies, from deadly diseases …

How uterine microbiota might be responsible for a receptive, fertile endometrium

M Benner, G Ferwerda, I Joosten… - Human reproduction …, 2018 - academic.oup.com
BACKGROUND Fertility depends on a receptive state of the endometrium, influenced by
hormonal and anatomical adaptations, as well as the immune system. Local and systemic …

Cervicovaginal bacteria are a major modulator of host inflammatory responses in the female genital tract

EH Byrne, KE Doherty, BA Bowman, HS Yamamoto… - Immunity, 2015 - cell.com
Colonization by Lactobacillus in the female genital tract is thought to be critical for
maintaining genital health. However, little is known about how genital microbiota influence …

The seminal microbiome in health and disease

S Altmäe, JM Franasiak, R Mändar - Nature Reviews Urology, 2019 - nature.com
Owing to the fact that there are more microbial than human cells in our body and that
humans contain more microbial than human genes, the microbiome has huge potential to …

Exposure to HIV-1 directly impairs mucosal epithelial barrier integrity allowing microbial translocation

A Nazli, O Chan, WN Dobson-Belaire, M Ouellet… - PLoS …, 2010 - journals.plos.org
While several clinical studies have shown that HIV-1 infection is associated with increased
permeability of the intestinal tract, there is very little understanding of the mechanisms …

Vulvovaginal Candida albicans infections: pathogenesis, immunity and vaccine prospects

A Cassone - BJOG: An International Journal of Obstetrics & …, 2015 - Wiley Online Library
Although a number of fungal species belonging to the genus C andida can cause acute
vulvovaginal infection (VVC), C andida albicans is by far the most prevalent etiological …

Targeting early infection to prevent HIV-1 mucosal transmission

AT Haase - Nature, 2010 - nature.com
Measures to prevent sexual mucosal transmission of human immunodeficiency virus (HIV)-1
are urgently needed to curb the growth of the acquired immunodeficiency syndrome (AIDS) …

Innate and adaptive immunity in female genital tract: cellular responses and interactions

CR Wira, JV Fahey, CL Sentman, PA Pioli… - Immunological …, 2005 - Wiley Online Library
The mucosal immune system in the female reproductive tract (FRT) has evolved to meet the
unique requirements of dealing with sexually transmitted bacterial and viral pathogens …

Cervical remodeling during pregnancy and parturition

B Timmons, M Akins, M Mahendroo - Trends in Endocrinology & …, 2010 - cell.com
Appropriate and timely cervical remodeling is key for successful birth. Premature cervical
opening can result in preterm birth which occurs in 12.5% of pregnancies. Research focused …