Primary surgery vs chemoradiation treatment of advanced-stage hypopharyngeal squamous cell carcinoma

BN Harris, VL Biron, P Donald… - … –Head & Neck …, 2015 - jamanetwork.com
Importance There is no consensus whether primary surgery followed by either adjuvant
radiotherapy (RT) or adjuvant chemoradiation (CRT) or definitive CRT should be the …

[引用][C] Cancer of the head and neck

J Myers, E Hanna - 2016 - Lippincott Williams & Wilkins

Accumulation, fractionation, and analysis of platinum in toxicologically affected tissues after cisplatin, oxaliplatin, and carboplatin administration

D Esteban-Fernández, JM Verdaguer… - Journal of analytical …, 2008 - academic.oup.com
Antitumoral Pt-containing drugs present side effects like nephrotoxicity and ototoxicity.
Several systematic experiments have been carried out with Wistar rats treated with cisplatin …

Squamous cell carcinoma of the hypopharynx: single-institution outcome analysis of a large cohort of patients treated with primary non-surgical approaches

T Gupta, S Chopra, JP Agarwal, SG Laskar… - Acta …, 2009 - Taylor & Francis
Introduction. Hypopharyngeal cancers have extensive submucosal spread, high risk of
nodal involvement and relatively high propensity of distant metastases. Contemporary …

Combating cancer by utilizing noble metallic nanostructures in combination with laser photothermal and X-ray radiotherapy

Z Kayani, N Islami, N Behzadpour, N Zahraie… - Journal of Drug Delivery …, 2021 - Elsevier
Conventional cancer therapy often fails for an insufficient therapeutic outcome, tumor
heterogeneity, and drug resistance. The past decade has witnessed that combination …

Transoral carbon-dioxide laser resection of hypopharyngeal carcinoma

HH Rudert, S Höft - European archives of oto-rhino-laryngology, 2003 - Springer
In hypopharyngeal carcinoma, open partial resection is rarely feasible because of the high
rate of chronic aspiration. Transoral laser surgery, however, is not associated with major …

Oxaliplatin induces immunogenic cell death in human and murine laryngeal cancer

J Wang, H Zhang, X Yin, Y Bian - Journal of Oncology, 2022 - Wiley Online Library
Background. Cisplatin resistance is observed in patients with laryngeal cancer. The present
study was designed to explore the efficacy of oxaliplatin on laryngeal cancer and elucidate …

Organ preservation with radiotherapy for T1‐T2 carcinoma of the pyriform sinus

RJ Amdur, WM Mendenhall, SP Stringer… - Head & …, 2001 - Wiley Online Library
Purpose To report long‐term results using radiotherapy with or without a planned neck
dissection for T1‐T2 carcinoma of the pyriform sinus. Methods An analysis of 101 patients …

[HTML][HTML] Long-term results of intensity-modulated radiotherapy concomitant with chemotherapy for hypopharyngeal carcinoma aimed at laryngeal preservation

WS Liu, CH Hsin, YH Chou, JT Liu, MF Wu, SW Tseng… - BMC cancer, 2010 - Springer
Background The objective of this retrospective study is to investigate laryngeal preservation
and long-term treatment results in hypopharyngeal carcinoma treated with intensity …

A contemporary review of indications for primary surgical care of patients with squamous cell carcinoma of the head and neck

CG Gourin, JT Johnson - The Laryngoscope, 2009 - Wiley Online Library
The success of organ preservation protocols in laryngeal cancer has led to an increase in
the use of primary chemoradiation in both laryngeal and extralaryngeal sites, despite a …