Precision medicine of obesity as an integral part of type 2 diabetes management–past, present, and future

L Szczerbinski, JC Florez - The Lancet Diabetes & Endocrinology, 2023 - thelancet.com
Obesity is a complex and heterogeneous condition that leads to various metabolic
complications, including type 2 diabetes. Unfortunately, for some, treatment options to date …

Precision medicine in adult and pediatric obesity: a clinical perspective

EM Bomberg, JR Ryder, RC Brundage… - Therapeutic …, 2019 - journals.sagepub.com
It remains largely unknown as to why some individuals experience substantial weight loss
with obesity interventions, while others receiving these same interventions do not. Person …

[HTML][HTML] Topiramate

KA Fariba, A Saadabadi - StatPearls [Internet], 2023 - ncbi.nlm.nih.gov
Objectives: Describe the mechanism of action of topiramate. Identify the indications of
topiramate. Review the appropriate monitoring of topiramate. Outline some interprofessional …

Approach to obesity in the older population

A Buch, Y Marcus, G Shefer, P Zimmet… - The Journal of Clinical …, 2021 - academic.oup.com
Until recently, weight loss in older obese people was feared because of ensuing muscle loss
and frailty. Facing overall increasing longevity, high rates of obesity in older individuals …

Controversial issues: A practical guide to the use of weight loss medications after bariatric surgery for weight regain or inadequate weight loss

FC Stanford - Surgery for Obesity and Related Diseases, 2019 - soard.org
Methods Before consideration of weight loss medications after weight loss surgery, it is
important to consider whether there is an anatomic reason for inadequate weight loss or …

[PDF][PDF] Borderline personality disorder and unmet needs

A Grambal, J Prasko, M Ociskova, M Slepecky… - Neuroendocrinol …, 2017 - researchgate.net
BACKGROUND: Borderline personality disorder (BPD) is a disabling psychiatric condition
with a chronic and challenging course. BPD is reflected as a disorder of self-regulation” and …

Pharmacotherapy for older people with obesity

LD Boyle, F Akbas, D Yazıcı, BM McGowan… - European Journal of …, 2024 - Elsevier
Rates of obesity continue to rise, including in older adults. Use of medication for obesity in
the elderly has been considered controversial, due to concerns around potential …

[HTML][HTML] Deriving Weight From Big Data: Comparison of Body Weight Measurement–Cleaning Algorithms

R Evans, J Burns, L Damschroder, A Annis… - JMIR Medical …, 2022 - medinform.jmir.org
Background: Patient body weight is a frequently used measure in biomedical studies, yet
there are no standard methods for processing and cleaning weight data. Conflicting …

The morphometrical and immunohistochemical investigation of the effect of topiramate on liver and the role of neuropeptide Y receptor in an obese female rat.

A BZ - Bratislava Medical Journal/Bratislavské Lekárske …, 2020 - search.ebscohost.com
OBJECTIVE: We aimed to investigate the possible effect of topiramate (TOP, 0.02
mg/kg/day) on the livers in a high-fat diet (HFD)-induced obesity rat model. The other …

Study on Efficacy of Topiramate: Impact on weight Loss in Obese patients

P Nithyakala, G Sathyaprabha… - Research Journal of …, 2021 - indianjournals.com
Obesity is a serious and growing problem worldwide, contributes greatly to morbidity and
mortality. This is a prospective-observational study of the weight loss on the efficacy of …