Studies have shown that infection, excessive coagulation, cytokine storm, leukopenia,
lymphopenia, hypoxemia and oxidative stress have also been observed in critically ill …

Individuals at high risk of developing seropositive rheumatoid arthritis (RA) can be identified
for translational research and disease prevention studies through the presence of highly …

The acute respiratory distress syndrome (ARDS) is an important cause of acute respiratory
failure that is often associated with multiple organ failure. Several clinical disorders can …

Lung epithelial cells are increasingly recognized to be active effectors of microbial defense,
contributing to both innate and adaptive immune function in the lower respiratory tract. As …

In 2005, the International Union of Basic and Clinical Pharmacology Committee on Receptor
Nomenclature and Drug Classification (NC-IUPHAR) published a catalog of all of the human …

During development, the human fetus accrues the highest proportion of fat of all mammals.
Precursors of fat lobules can be found at week 14 of pregnancy. Thereafter, they expand …

Lung macrophages are long living cells with broad differentiation potential, which reside in
the lung interstitium and alveoli or are organ-recruited upon inflammatory stimuli. A role of …

Considerable progress has been made in understanding the basic mechanisms that
regulate fluid and protein exchange across the endothelial and epithelial barriers of the lung …

In the healthy gastrointestinal tract, homeostasis is an active process that requires a careful
balance of host responses to the enteric luminal contents. Intestinal macrophages and …

Diseases of failed inflammation resolution are common and largely incurable. Therapeutic
induction of inflammation resolution is an attractive strategy to bring about healing without …