Vegan diet health benefits in metabolic syndrome
G Marrone, C Guerriero, D Palazzetti, P Lido, A Marolla… - Nutrients, 2021 - mdpi.com
Plant-based diets (PBDs) are increasingly consumed by the Italian population and around
the world. In particular, among PBDs, the vegan diet is a food pattern characterized by the …
the world. In particular, among PBDs, the vegan diet is a food pattern characterized by the …
Phosphorylation: implications in cancer
V Singh, M Ram, R Kumar, R Prasad, BK Roy… - The protein journal, 2017 - Springer
Post translational modifications (PTMs) are involved in variety of cellular activities and
phosphorylation is one of the most extensively studied PTM, which regulates a number of …
phosphorylation is one of the most extensively studied PTM, which regulates a number of …
LPS/TLR4 signal transduction pathway
The stimulation of Toll-like receptor 4 (TLR4) by lipopolysaccharide (LPS) induces the
release of critical proinflammatory cytokines that are necessary to activate potent immune …
release of critical proinflammatory cytokines that are necessary to activate potent immune …
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
PJ Roberts, CJ Der - Oncogene, 2007 - nature.com
Mitogen-activated protein kinase (MAPK) cascades are key signaling pathways involved in
the regulation of normal cell proliferation, survival and differentiation. Aberrant regulation of …
the regulation of normal cell proliferation, survival and differentiation. Aberrant regulation of …
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
LAJ O'Neill, AG Bowie - Nature Reviews Immunology, 2007 - nature.com
Signalling by Toll-like receptors (TLRs) involves five adaptor proteins known as MyD88,
MAL, TRIF, TRAM and SARM. Recent insights have revealed additional functions for MyD88 …
MAL, TRIF, TRAM and SARM. Recent insights have revealed additional functions for MyD88 …
Importance of glial activation in neuropathic pain
J Mika, M Zychowska, K Popiolek-Barczyk… - European journal of …, 2013 - Elsevier
Glia plays a crucial role in the maintenance of neuronal homeostasis in the central nervous
system. The microglial production of immune factors is believed to play an important role in …
system. The microglial production of immune factors is believed to play an important role in …
Targeting Toll-like receptors: emerging therapeutics?
EJ Hennessy, AE Parker, LAJ O'neill - Nature reviews Drug discovery, 2010 - nature.com
There is a growing interest in the targeting of Toll-like receptors (TLRs) for the prevention
and treatment of cancer, rheumatoid arthritis, inflammatory bowel disease and systemic …
and treatment of cancer, rheumatoid arthritis, inflammatory bowel disease and systemic …
Modeling inflammation in zebrafish for the development of anti-inflammatory drugs
Y Xie, AH Meijer, MJM Schaaf - Frontiers in cell and developmental …, 2021 - frontiersin.org
Dysregulation of the inflammatory response in humans can lead to various inflammatory
diseases, like asthma and rheumatoid arthritis. The innate branch of the immune system …
diseases, like asthma and rheumatoid arthritis. The innate branch of the immune system …
A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders
J Kim, YN Cha, YJ Surh - Mutation Research/Fundamental and Molecular …, 2010 - Elsevier
Nuclear factor-erythroid 2-related factor-2 (Nrf2) is a key transcription factor that plays a
central role in cellular defense against oxidative and electrophilic insults by timely induction …
central role in cellular defense against oxidative and electrophilic insults by timely induction …
Interferons at age 50: past, current and future impact on biomedicine
EC Borden, GC Sen, G Uze, RH Silverman… - Nature reviews Drug …, 2007 - nature.com
The family of interferon (IFN) proteins has now more than reached the potential envisioned
by early discovering virologists: IFNs are not only antivirals with a spectrum of clinical …
by early discovering virologists: IFNs are not only antivirals with a spectrum of clinical …