Monogenic diabetes refers to diabetes mellitus (DM) caused by a mutation in a single gene
and accounts for approximately 1%–5% of diabetes. Correct diagnosis is clinically critical for …

Nonalcoholic Fatty Liver Disease (NAFLD) represents the leading cause of liver disease in
developed countries but its diffusion is currently also emerging in Asian countries, in South …

The current and long-term health of 14.4 million children and adolescents is affected by
obesity, 1, 2 making it one of the most common pediatric chronic diseases. 3–5 Long …

Objective Sugar-sweetened beverage (SSB) consumption had substantially increased
across successive US birth cohorts until 2000, and adolescents and young adults under age …

Background Childhood overweight is associated with an increased risk of type 2 diabetes in
adulthood. We investigated whether remission of overweight before early adulthood reduces …

The increased prevalence of adolescent obesity and associated short-term and long-term
complications emphasize the need for effective treatment. In this Review, we aim to describe …

Obesity in childhood is the main determinant of whole body reduced insulin sensitivity. This
association has been demonstrated in multiple adult and pediatric cohorts. The mechanistic …

Background: The prevalence of type 2 diabetes (DM) in children is disturbingly increasing in
parallel with the increasing childhood obesity. Better knowledge regarding the …

Insulin resistance (IR) is insulin failure in normal plasma levels to adequately stimulate
glucose uptake by the peripheral tissues. IR is becoming more common in children and …

The intent of this review is to critically consider the data that support the concept of
programming and its implications. Birth weight and growth trajectories during childhood are …