Glycoconjugates are major constituents of mammalian cells that are formed via covalent
conjugation of carbohydrates to other biomolecules like proteins and lipids and often …

Methods for site-selective transformations of hydroxyl groups in carbohydrate derivatives are
reviewed. The construction of oligosaccharides of defined connectivity hinges on such …

Bacteria produce a wide range of exopolysaccharides which are synthesized via different
biosynthesis pathways. The genes responsible for synthesis are often clustered within the …

Glycosylation is one of the most prevalent posttranslational modifications that profoundly
affects the structure and functions of proteins in a wide variety of biological recognition …

A systematic analysis of all naturally-occurring glycosylated bacterial secondary metabolites
reported in the scientific literature up through early 2013 is presented. This comprehensive …

Synthetic oligosaccharides and glycoconjugates are increasingly used as probes for
biological research and as lead compounds for drug and vaccine discovery. These …

Many biologically active small‐molecule natural products produced by microorganisms
derive their activities from sugar substituents. Changing the structures of these sugars can …

A new focus on glycoscience, a field that explores the structures and functions of sugars,
promises great advances in areas as diverse as medicine, energy generation, and materials …

Carbohydrates have been shown to play important roles in biological processes. The pace
of development in carbohydrate research is, however, relatively slow due to the problems …

A robust platform for facile defined glycan synthesis does not exist. Yet the need for such
technology has never been greater as researchers seek to understand the full scope of …