Tachykinins and calcitonin gene-related peptide (CGRP) as co-transmitters released from peripheral endings of sensory nerves

CA Maggi - Progress in neurobiology, 1995 - Elsevier
2. Tachykinins and CGRP in primary afferent neurons 2.1. Synthesis and expression of
tachykinins 2.2. Svnthesis and exnression of CGRP 2.3. Co-localization of tachykinins and …

Peptidergic sensory neurons in the control of vascular functions: mechanisms and significance in the cutaneous and splanchnic vascular beds

P Holzer - Reviews of Physiology, Biochemistry and …, 2005 - Springer
Tissue blood flow is regulated by local autoregulatory mechanisms, factors released from
endothelial cells, hormones and neural factors. The role of autonomic neurons, notably of …

Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia

NM Page, RJ Woods, SM Gardiner, K Lomthaisong… - Nature, 2000 - nature.com
Pre-eclampsia is a principal cause of maternal morbidity and mortality, affecting 5–10% of
first pregnancies worldwide. Manifestations include increased blood pressure, proteinuria …

Pharmacodynamic evaluation of Lys5, MeLeu9, Nle10-NKA(4–10) prokinetic effects on bladder and colon activity in acute spinal cord transected and spinally intact …

FA Kullmann, M Katofiasc, KB Thor… - … Schmiedeberg's archives of …, 2017 - Springer
The purpose of this study was to determine feasibility of a novel therapeutic approach to
drug-induced voiding after spinal cord injury (SCI) using a well-characterized, peptide …

Variation in mRNA expression of alpha-adrenergic, neurokinin and muscarinic receptors amongst four arteries of the rat

JK Phillips, M Vidovic, CE Hill - Journal of the autonomic nervous system, 1997 - Elsevier
Different mechanisms mediate constriction and dilation in different vascular beds. We have
used reverse transcription-polymerase chain reaction to investigate whether specific …

Antifibrotic Drugs against Idiopathic Pulmonary Fibrosis and Pulmonary Fibrosis Induced by COVID-19: Therapeutic Approaches and Potential Diagnostic Biomarkers

A Perez-Favila, I Garza-Veloz… - International Journal of …, 2024 - mdpi.com
The COVID-19 pandemic has had a significant impact on the health and economy of the
global population. Even after recovery from the disease, post-COVID-19 symptoms, such as …

Neurokinins produce selective venoconstriction via NK-3 receptors in the rat mesenteric vascular bed

P D'Orléans-Juste, A Claing, S Télémaque… - European journal of …, 1991 - Elsevier
The vasoactive properties of the neurokinins (substance P (SP), neurokinin A (NKA),
neurokinin B (NKB)) and some selective analogues were assessed in the arterial and …

Cardiovascular and behavioural effects of centrally administered tachykinins in the rat: characterization of receptors with selective antagonists

P Picard, D Regoli, R Couture - British journal of pharmacology, 1994 - Wiley Online Library
1 The effects of intracerebroventricular (icv) injection of selective and potent NK1 (RP
67580), NK2 (SR 48968) and NK3 (R 486,[Trp7, β‐Ala8] NKA (4–10)) receptor antagonists …

Role of Sensory Nerves in Pulmonary Fibrosis

CE Norton - International Journal of Molecular Sciences, 2024 - mdpi.com
Pulmonary fibrosis results from the deposition and proliferation of extracellular matrix
components in the lungs. Despite being an airway disorder, pulmonary fibrosis also has …

The effect of intravenous maropitant on blood pressure in healthy awake and anesthetized dogs

TT Chi, BL Hay Kraus - Plos one, 2020 - journals.plos.org
Objective To evaluate the effects of intravenous maropitant on arterial blood pressure in
healthy dogs while awake and under general anesthesia. Design Experimental crossover …