Pulmonary arterial hypertension is a progressive syndrome based on diverse aetiologies,
which is characterized by a persistent increase in pulmonary vascular resistance and …

Canonical or classical transient receptor potential channel 6 (TRPC6) is a Ca2+-permeable
non-selective cation channel that is widely expressed in the heart, lung, and vascular …

Pulmonary arterial hypertension (PAH) is characterized by adverse remodeling of
pulmonary arteries. Although the origin of the disease and its underlying pathophysiology …

For the first time, the present study unravels a cardiospecific therapeutic approach for
Pulmonary Arterial Hypertension (PAH), a disease with a very poor prognosis and high …

Diagnosis of pulmonary arterial hypertension (PAH) is difficult due to the lack of specific
clinical symptoms and biomarkers, especially at early stages. We compared plasma …

Ethnopharmacological relevance The stem bark of Terminalia arjuna (Roxb.) is widely used
in Ayurveda in various cardiovascular diseases. Many animal and clinical studies have …

Pulmonary arterial hypertension (PAH) is a progressive vascular remodelling disease where
patients ultimately die from heart failure. Increased production of vasoconstrictors …

Sildenafil citrate is a selective phosphodiesterase-5 inhibitor used for the treatment for
erectile dysfunction and pulmonary hypertension. The delivery of sildenafil directly to the …

Intra‐amniotic injection of lipopolysaccharide (LPS) induces pulmonary hypertension in
newborn rats. This study was designed to test whether human mesenchymal stem cells …

Background Obesity and pulmonary hypertension (PH) share common characteristics, such
as augmented inflammation and oxidative stress. However, the exact role of obesity in the …