Engineering microbial consortia: a new frontier in synthetic biology

K Brenner, L You, FH Arnold - Trends in biotechnology, 2008 - cell.com
Microbial consortia are ubiquitous in nature and are implicated in processes of great
importance to humans, from environmental remediation and wastewater treatment to …

Co-culture systems and technologies: taking synthetic biology to the next level

L Goers, P Freemont, KM Polizzi - Journal of The Royal …, 2014 - royalsocietypublishing.org
Co-culture techniques find myriad applications in biology for studying natural or synthetic
interactions between cell populations. Such techniques are of great importance in synthetic …

Synthetic quorum-sensing circuit to control consortial biofilm formation and dispersal in a microfluidic device

SH Hong, M Hegde, J Kim, X Wang… - Nature …, 2012 - nature.com
To utilize biofilms for chemical transformations in biorefineries they need to be controlled
and replaced. Previously, we engineered the global regulator Hha and cyclic diguanylate …

Stochastic simulations of a synthetic bacteria-yeast ecosystem

K Biliouris, D Babson, C Schmidt-Dannert… - BMC systems …, 2012 - Springer
Background The field of synthetic biology has greatly evolved and numerous functions can
now be implemented by artificially engineered cells carrying the appropriate genetic …

Analysis of productivity and stability of synthetic microbial communities

S Di, A Yang - Journal of the Royal Society Interface, 2019 - royalsocietypublishing.org
Bioreactors that employ a synthetic microbial community hold potential to overcome
limitations of those based on a single species, which embrace a higher level of complexity …

Artificially constructed quorum-sensing circuits are used for subtle control of bacterial population density

Z Wang, X Wu, J Peng, Y Hu, B Fang, S Huang - PLoS One, 2014 - journals.plos.org
Vibrio fischeri is a typical quorum-sensing bacterium for which lux box, luxR, and luxI have
been identified as the key elements involved in quorum sensing. To decode the quorum …

Directed evolution of LuxI for enhanced OHHL production

PKR Kambam, DJ Sayut, Y Niu… - Biotechnology and …, 2008 - Wiley Online Library
Quorum sensing is a common mechanism used by bacteria to coordinate population
behavior, and is involved in a variety of biological processes, such as bioluminescence …

Evolution of resistance to quorum quenching in digital organisms

BE Beckmann, DB Knoester, BD Connelly, CM Waters… - Artificial life, 2012 - direct.mit.edu
Quorum sensing (QS) is a collective behavior whereby actions of individuals depend on the
density of the surrounding population. Bacteria use QS to trigger secretion of digestive …

Maximizing microbial degradation of perchlorate using a genetic algorithm: media optimization

KH Kucharzyk, RL Crawford, AJ Paszczynski… - Journal of …, 2012 - Elsevier
Microbial communities are under constant influence of physical and chemical components in
ecosystems. Shifts in conditions such as pH, temperature or carbon source concentration …

Prokaryotic bio-inspired system

M Samie, G Dragffy, A Popescu… - 2009 NASA/ESA …, 2009 - ieeexplore.ieee.org
This paper presents a novel bio-inspired artificial system that is based on biological
prokaryotic organisms and their artificial model, and proposes a new type of fault tolerant …