The nuclear paraspeckle assembly transcript 1 (NEAT1) is a long non-coding RNA (lncRNA)
that is upregulated in a variety of human cancer types. Increasing evidence has shown that …

Long noncoding RNAs (lncRNAs) are RNA molecules involved in gene regulation at
transcriptional, post-transcriptional, and epigenetic levels. LncRNAs participate in regulating …

Perineural invasion (PNI) is a pathologic feature of pancreatic cancer and is associated with
poor outcomes, metastasis, and recurrence in pancreatic cancer patients. However, the …

Pancreatic adenocarcinoma remains a leading cause of cancer‐related deaths. In order to
develop appropriate therapeutic and prognostic tools, a comprehensive mapping of the …

Platelets have been recognized as key players in hemostasis, thrombosis, and cancer.
Preclinical and clinical researches evidenced that tumorigenesis and metastasis can be …

(1) Background: This investigation aimed at developing a series of c-Met-targeting
cabozantinib-based PROTACs.(2) Methods: Purification of intermediate and target …

Simple Summary CTHRC1 is a protein with pro-tumoral effects that is highly expressed in
tumors. We found that cancer stroma is the major source of CTHRC1 secretion in pancreatic …

Pancreatic ductal adenocarcinoma (PDA) is highly aggressive and has few treatment
options. To personalize therapy, it is critical to delineate molecular subtypes and understand …

Pancreatic cancer (PC) presents extremely aggressive tumours and is associated with poor
survival. This is attributed to the unique features of the tumour microenvironment (TME) …

Simple Summary Savolitinib is a highly specific inhibitor of the MET tyrosine kinase. Both
preclinical and clinical studies have shown its potential as a treatment for various cancers …