Aging and DNA methylation

M Jung, GP Pfeifer - BMC biology, 2015 - Springer
In this Opinion article, we summarize how changes in DNA methylation occur during aging
in mammals and discuss examples of how such events may contribute to the aging process …

Biomarkers of nutrition and health: new tools for new approaches

C Picó, F Serra, AM Rodríguez, J Keijer, A Palou - Nutrients, 2019 - mdpi.com
A main challenge in nutritional studies is the valid and reliable assessment of food intake, as
well as its effects on the body. Generally, food intake measurement is based on self-reported …

Obesity may accelerate the aging process

V Salvestrini, C Sell, A Lorenzini - Frontiers in endocrinology, 2019 - frontiersin.org
Lines of evidence from several studies have shown that increases in life expectancy are now
accompanied by increased disability rate. The expanded lifespan of the aging population …

Epigenome-wide association study identifies TXNIP gene associated with type 2 diabetes mellitus and sustained hyperglycemia

C Soriano-Tárraga, J Jiménez-Conde… - Human molecular …, 2016 - academic.oup.com
Type 2 diabetes mellitus (DM) is an established risk factor for a wide range of vascular
diseases, including ischemic stroke (IS). Glycated hemoglobin A1c (HbA1c), a marker for …

The mechanism and function of epigenetics in uterine leiomyoma development

Q Yang, A Mas, MP Diamond… - Reproductive …, 2016 - journals.sagepub.com
Uterine leiomyomas, also known as uterine fibroids, are the most common pelvic tumors,
occurring in nearly 70% of all reproductive-aged women and are the leading indication for …

Potential role of circulating microRNAs (486-5p, 497, 509-5p and 605) in metabolic syndrome Egyptian male patients

M Bakr Zaki, AI Abulsoud, AM Elsisi… - … syndrome and obesity …, 2019 - Taylor & Francis
Objective: This study aims to evaluate the expression pattern of circulating microRNAs (miR)-
486-5p, miR-497, miR-509-5p, and miR-605 in the serum of metabolic syndrome (MetS) …

The role of DNA methylation in the pathogenesis of type 2 diabetes mellitus

SAH Ahmed, SA Ansari, EPK Mensah-Brown… - Clinical …, 2020 - Springer
Diabetes mellitus (DM) is a chronic condition characterised by β cell dysfunction and
persistent hyperglycaemia. The disorder can be due to the absence of adequate pancreatic …

Zinc finger readers of methylated DNA

NO Hudson, BA Buck-Koehntop - Molecules, 2018 - mdpi.com
DNA methylation is a prevalent epigenetic modification involved in regulating a number of
essential cellular processes, including genomic accessibility and transcriptional outcomes …

Epigenomic and enhancer dysregulation in uterine leiomyomas

OW Mlodawska, P Saini, JB Parker… - Human …, 2022 - academic.oup.com
BACKGROUND Uterine leiomyomas, also known as uterine fibroids or myomas, are the
most common benign gynecological tumors and are found in women of reproductive and …

[PDF][PDF] Biomarkers: background, classification and guidelines for applications in nutritional epidemiology

D Corella, JM Ordovás - Nutricion hospitalaria, 2015 - redalyc.org
One of the main problems in nutritional epidemiology is to assess food intake as well as
nutrient/food component intake to a high level of validity and reliability. To help in this …