Magnetic resonance texture analysis reveals stagewise nonlinear alterations of the frontal gray matter in patients with early psychosis

SY Moon, H Park, W Lee, S Lee, SK Lho, M Kim… - Molecular …, 2023 - nature.com
Although gray matter (GM) abnormalities are present from the early stages of psychosis,
subtle/miniscule changes may not be detected by conventional volumetry. Texture analysis …

A systematic review of multisensory cognitive–affective integration in schizophrenia

HH Tseng, MG Bossong, G Modinos, KM Chen… - Neuroscience & …, 2015 - Elsevier
The etymology of schizophrenia implies poor functional integration of sensory, cognitive and
affective processes. Multisensory integration (MSI) is a spontaneous perceptual–cognitive …

Neuroanatomical heterogeneity and homogeneity in individuals at clinical high risk for psychosis

H Baldwin, J Radua, M Antoniades, SS Haas… - Translational …, 2022 - nature.com
Abstract Individuals at Clinical High Risk for Psychosis (CHR-P) demonstrate heterogeneity
in clinical profiles and outcome features. However, the extent of neuroanatomical …

Brain structural abnormalities as potential markers for detecting individuals with ultra-high risk for psychosis: a systematic review and meta-analysis

Y Ding, Y Ou, P Pan, X Shan, J Chen, F Liu, J Zhao… - Schizophrenia …, 2019 - Elsevier
Objective This study aims to determine whether structural alterations can be used as
neuroimaging markers to detect individuals with ultra-high risk (UHR) for psychosis for the …

Reduced inferior frontal gyrus activation during response inhibition to emotional stimuli in youth at high risk of bipolar disorder

G Roberts, MJ Green, M Breakspear, C McCormack… - Biological …, 2013 - Elsevier
BACKGROUND: Functional brain imaging of young people at increased genetic risk for
bipolar disorder provides a means of identifying potential endophenotypes for this condition …

Relationship between brain glutamate levels and clinical outcome in individuals at ultra high risk of psychosis

A Egerton, JM Stone, CA Chaddock… - …, 2014 - nature.com
Alterations in brain glutamate levels may be associated with psychosis risk, but the
relationship to clinical outcome in at-risk individuals is unknown. Glutamate concentration …

Translating research findings into clinical practice: a systematic and critical review of neuroimaging-based clinical tools for brain disorders

C Scarpazza, M Ha, L Baecker, R Garcia-Dias… - Translational …, 2020 - nature.com
A pivotal aim of psychiatric and neurological research is to promote the translation of the
findings into clinical practice to improve diagnostic and prognostic assessment of individual …

Reduced cortical volume and elevated astrocyte density in rats chronically treated with antipsychotic drugs—linking magnetic resonance imaging findings to cellular …

AC Vernon, WR Crum, JP Lerch, W Chege… - Biological …, 2014 - Elsevier
Background Increasing evidence suggests that antipsychotic drugs (APD) might affect brain
structure directly, particularly the cerebral cortex. However, the precise anatomical loci of …

Improved individualized prediction of schizophrenia in subjects at familial high risk, based on neuroanatomical data, schizotypal and neurocognitive features

E Zarogianni, AJ Storkey, EC Johnstone… - Schizophrenia …, 2017 - Elsevier
To date, there are no reliable markers for predicting onset of schizophrenia in individuals at
high risk (HR). Substantial promise is, however, shown by a variety of pattern classification …

Increased occipital gyrification and development of psychotic disorders in individuals with an at-risk mental state: a multicenter study

D Sasabayashi, Y Takayanagi, T Takahashi, S Koike… - Biological …, 2017 - Elsevier
Background Anomalies of brain gyrification have been reported in schizophrenia, possibly
reflecting its neurodevelopmental pathology. However, it remains elusive whether …