Magnetic resonance texture analysis reveals stagewise nonlinear alterations of the frontal gray matter in patients with early psychosis
Although gray matter (GM) abnormalities are present from the early stages of psychosis,
subtle/miniscule changes may not be detected by conventional volumetry. Texture analysis …
subtle/miniscule changes may not be detected by conventional volumetry. Texture analysis …
A systematic review of multisensory cognitive–affective integration in schizophrenia
The etymology of schizophrenia implies poor functional integration of sensory, cognitive and
affective processes. Multisensory integration (MSI) is a spontaneous perceptual–cognitive …
affective processes. Multisensory integration (MSI) is a spontaneous perceptual–cognitive …
Neuroanatomical heterogeneity and homogeneity in individuals at clinical high risk for psychosis
Abstract Individuals at Clinical High Risk for Psychosis (CHR-P) demonstrate heterogeneity
in clinical profiles and outcome features. However, the extent of neuroanatomical …
in clinical profiles and outcome features. However, the extent of neuroanatomical …
Brain structural abnormalities as potential markers for detecting individuals with ultra-high risk for psychosis: a systematic review and meta-analysis
Y Ding, Y Ou, P Pan, X Shan, J Chen, F Liu, J Zhao… - Schizophrenia …, 2019 - Elsevier
Objective This study aims to determine whether structural alterations can be used as
neuroimaging markers to detect individuals with ultra-high risk (UHR) for psychosis for the …
neuroimaging markers to detect individuals with ultra-high risk (UHR) for psychosis for the …
Reduced inferior frontal gyrus activation during response inhibition to emotional stimuli in youth at high risk of bipolar disorder
BACKGROUND: Functional brain imaging of young people at increased genetic risk for
bipolar disorder provides a means of identifying potential endophenotypes for this condition …
bipolar disorder provides a means of identifying potential endophenotypes for this condition …
Relationship between brain glutamate levels and clinical outcome in individuals at ultra high risk of psychosis
A Egerton, JM Stone, CA Chaddock… - …, 2014 - nature.com
Alterations in brain glutamate levels may be associated with psychosis risk, but the
relationship to clinical outcome in at-risk individuals is unknown. Glutamate concentration …
relationship to clinical outcome in at-risk individuals is unknown. Glutamate concentration …
Translating research findings into clinical practice: a systematic and critical review of neuroimaging-based clinical tools for brain disorders
A pivotal aim of psychiatric and neurological research is to promote the translation of the
findings into clinical practice to improve diagnostic and prognostic assessment of individual …
findings into clinical practice to improve diagnostic and prognostic assessment of individual …
Reduced cortical volume and elevated astrocyte density in rats chronically treated with antipsychotic drugs—linking magnetic resonance imaging findings to cellular …
AC Vernon, WR Crum, JP Lerch, W Chege… - Biological …, 2014 - Elsevier
Background Increasing evidence suggests that antipsychotic drugs (APD) might affect brain
structure directly, particularly the cerebral cortex. However, the precise anatomical loci of …
structure directly, particularly the cerebral cortex. However, the precise anatomical loci of …
Improved individualized prediction of schizophrenia in subjects at familial high risk, based on neuroanatomical data, schizotypal and neurocognitive features
E Zarogianni, AJ Storkey, EC Johnstone… - Schizophrenia …, 2017 - Elsevier
To date, there are no reliable markers for predicting onset of schizophrenia in individuals at
high risk (HR). Substantial promise is, however, shown by a variety of pattern classification …
high risk (HR). Substantial promise is, however, shown by a variety of pattern classification …
Increased occipital gyrification and development of psychotic disorders in individuals with an at-risk mental state: a multicenter study
D Sasabayashi, Y Takayanagi, T Takahashi, S Koike… - Biological …, 2017 - Elsevier
Background Anomalies of brain gyrification have been reported in schizophrenia, possibly
reflecting its neurodevelopmental pathology. However, it remains elusive whether …
reflecting its neurodevelopmental pathology. However, it remains elusive whether …