Extended path expressions of XML

M Murata - Proceedings of the twentieth ACM SIGMOD-SIGACT …, 2001 - dl.acm.org
Query languages for XML often use path expressions to locate elements in XML documents.
Path expressions are regular expressions such that underlying alphabets represent …

Polymorphisms of interferon‐λ4 and IL28B – effects on treatment response to interferon/ribavirin in patients with chronic hepatitis C

AF Stättermayer, R Strassl, A Maieron… - Alimentary …, 2014 - Wiley Online Library
Summary Background The IL28B genotype in rs12979860 predicts success of
peginterferon/ribavirin (PEG/RBV) therapy in patients with chronic hepatitis C (CHC) …

Immune control and failure in HCV infection—tipping the balance

LB Dustin, SB Cashman… - Journal of leukocyte …, 2014 - academic.oup.com
Despite the development of potent antiviral drugs, HCV remains a global health problem;
global eradication is a long way off. In this review, we discuss the immune response to HCV …

Spontaneous viral load decline and subsequent clearance of chronic hepatitis C virus in postpartum women correlates with favorable interleukin-28B gene allele

M Hashem, R Jhaveri, DA Saleh… - Clinical Infectious …, 2017 - academic.oup.com
Background Postpartum hepatitis C viral (HCV) load decline followed by spontaneous
clearance has been previously described. Herein we identify predictors for viral decline in a …

[HTML][HTML] Identification of improved IL28B SNPs and haplotypes for prediction of drug response in treatment of hepatitis C using massively parallel sequencing in a …

KR Smith, V Suppiah, K O'Connor, T Berg, M Weltman… - Genome medicine, 2011 - Springer
Background The hepatitis C virus (HCV) infects nearly 3% of the World's population, causing
severe liver disease in many. Standard of care therapy is currently pegylated interferon …

Hepatitis C treatment: an incipient therapeutic revolution

AS deLemos, RT Chung - Trends in Molecular Medicine, 2014 - cell.com
An exciting paradigm shift is occurring in the treatment of hepatitis C virus (HCV). We now
have the capacity to specifically target therapy to HCV proteins, and thereby directly interrupt …

[HTML][HTML] Interferon-λ4 (IFNL4) Transcript Expression in Human Liver Tissue Samples

A Amanzada, W Kopp, U Spengler, G Ramadori… - PloS one, 2013 - journals.plos.org
Eradication of hepatitis C virus (HCV) infection, both spontaneous and treatment-induced, is
marked by the wildtype allele C of a single nucleotide polymorphism upstream of the IL28B …

[PDF][PDF] Natural killer inhibitory receptor expression associated with treatment failure and interleukin‐28B genotype in patients with chronic hepatitis C

L Golden‐Mason, KM Bambha, L Cheng… - …, 2011 - Wiley Online Library
Natural killer (NK) cells constitute a first line of defense against viral infections; their function
is governed by the integration of signals from multiple activating and inhibitory surface …

genetic factors that modify the outcome of viral hepatitis

AF Stättermayer, T Scherzer… - Alimentary …, 2014 - Wiley Online Library
Background Genetic factors can play an important role for treatment response and disease
progression in chronic viral hepatitis. Aim To review the influence of host genetic factors on …

Effect of immune pressure on hepatitis C virus evolution: insights from a single-source outbreak

S Merani, D Petrovic, I James, A Chopra, D Cooper… - Hepatology, 2011 - journals.lww.com
The host's immune response to hepatitis C virus (HCV) can result in the selection of
characteristic mutations (adaptations) that enable the virus to escape this response. The …