In chemical biology research, various fluorescent probes have been developed and used to
visualize target proteins or molecules in living cells and tissues, yet there are limitations to …

All molecules consist of chemical bonds, and much can be learned from mapping the
spatiotemporal dynamics of these bonds. Since its invention a decade ago, stimulated …

Combining immune checkpoint blockade (ICB) therapy with photodynamic therapy (PDT)
holds great potential in treating immunologically “cold” tumors, but photo-generated reactive …

The advent of image-activated cell sorting and imaging-based cell picking has advanced our
knowledge and exploitation of biological systems in the last decade. Unfortunately, they …

Stimulated Raman scattering (SRS) microscopy has shown enormous potential in revealing
molecular structures, dynamics, and couplings in complex systems. However, the sensitivity …

Raman spectroscopy is an increasingly popular technique in many areas, including biology
and medicine. It is based on Raman scattering, a phenomenon in which incident photons …

Stimulated Raman scattering (SRS) describes a family of techniques first discovered and
developed in the 1960s. Whereas the nascent history of the technique is parallel to that of …

Cells are the basic units of all living matter which harness the flow of energy to drive the
processes of life. While the biochemical networks involved in energy transduction are well …

Optical microscopy techniques have emerged as a cornerstone of biomedical research,
capable of probing the cellular functions of a vast range of substrates, whilst being minimally …

Cells and tissues often display pronounced spatial and dynamical metabolic heterogeneity.
Common glucose-imaging techniques report glucose uptake or catabolism activity, yet do …