Signal transduction inhibitors
H Rönnberg - Therapeutic Strategies in Veterinary Oncology, 2023 - cabidigitallibrary.org
5 Antimetastatic Therapy Page 1 5 Antimetastatic Therapy NICOLE S. AMATO* Ethos
Veterinary Health, Woburn, Massachusetts, USA Introduction The ability of cancer cells to …
Veterinary Health, Woburn, Massachusetts, USA Introduction The ability of cancer cells to …
Tumor cell dormancy: Molecular mechanisms, and pharmacological approaches to target dormant cells for countering tumor
Advancements in oncology have resulted in significant improvement in clinical outputs for
cancer patients. However, Cancer recurrence after initial therapeutic response remains a …
cancer patients. However, Cancer recurrence after initial therapeutic response remains a …
Assessing a novel 3D assay system for drug screening against OS metastasis
N Koons, N Amato, S Sauer, D Warshawsky, D Barkan… - Pharmaceuticals, 2021 - mdpi.com
Osteosarcoma (OS) is an aggressive mesenchymal cell tumor that carries a poor long-term
prognosis. Despite definitive surgery for the primary tumor and adjuvant chemotherapy …
prognosis. Despite definitive surgery for the primary tumor and adjuvant chemotherapy …
Carbon Nanomaterials: Emerging Roles in Immuno-Oncology
B Patrick, T Akhtar, R Kousar, CC Huang… - International Journal of …, 2023 - mdpi.com
Cancer immunotherapy has made breakthrough progress in cancer treatment. However,
only a subset of patients benefits from immunotherapy. Given their unique structure …
only a subset of patients benefits from immunotherapy. Given their unique structure …
[HTML][HTML] Splicing inhibition mediated by reduced splicing factors and helicases is associated with the cellular response of lung cancer cells to cisplatin
L Wang, N Yin, W Shi, Y Xie, J Yi, Z Tang, J Tang… - Computational and …, 2024 - Elsevier
Lung cancer's mortality is predominantly linked to post-chemotherapy recurrence, driven by
the reactivation of dormant cancer cells. Despite the critical role of these reactivated cells in …
the reactivation of dormant cancer cells. Despite the critical role of these reactivated cells in …
Dual FGFR-targeting and pH-activable Ruthenium-Peptide Conjugates for targeted therapy of Breast Cancer
JF Machado, M Sá, I Pires, MT da Silva… - Dalton …, 2024 - pubs.rsc.org
Dysregulation of Fibroblast Growth Factor Receptors (FGFRs) signaling has been
associated with breast cancer, yet employing FGFR-targeted delivery systems to improve the …
associated with breast cancer, yet employing FGFR-targeted delivery systems to improve the …
[HTML][HTML] Mini-Review: Can the Metastatic Cascade Be Inhibited by Targeting CD147/EMMPRIN to Prevent Tumor Recurrence?
MA Rahat - Frontiers in Immunology, 2022 - frontiersin.org
Solid tumors metastasize very early in their development, and once the metastatic cell is
lodged in a remote organ, it can proliferate to generate a metastatic lesion or remain …
lodged in a remote organ, it can proliferate to generate a metastatic lesion or remain …
Immunophenotype rearrangement in response to tumor excision may be related to the risk of biochemical recurrence in prostate cancer patients
P Bosas, G Zaleskis, D Dabkevičiene… - Journal of Clinical …, 2021 - mdpi.com
Background: Prostate cancer (PCa) is known to exhibit a wide spectrum of aggressiveness
and relatively high immunogenicity. The aim of this study was to examine the effect of tumor …
and relatively high immunogenicity. The aim of this study was to examine the effect of tumor …
The Potential of Integrative Cancer Treatment Using Melatonin and the Challenge of Heterogeneity in Population-Based Studies: A Case Report of Colon Cancer and …
E Smorodin, V Chuzmarov, T Veidebaum - Current Oncology, 2024 - mdpi.com
Melatonin is a multifunctional hormone regulator that maintains homeostasis through
circadian rhythms, and desynchronization of these rhythms can lead to gastrointestinal …
circadian rhythms, and desynchronization of these rhythms can lead to gastrointestinal …
具有休眠特征的播散肿瘤细胞体内外研究模型的建立及应用
阙祖俊, 刘佳君, 田建辉 - 肿瘤防治研究, 2023 - zlfzyj.com
摘要术后无症状的早期癌症(肺癌) 患者的转移靶器官中已经潜伏有处于休眠状态的播散肿瘤
细胞(DTCs), 其增殖是导致临床转移发生的关键环节. 开发维持DTCs 休眠或根除休眠DTCs …
细胞(DTCs), 其增殖是导致临床转移发生的关键环节. 开发维持DTCs 休眠或根除休眠DTCs …