Taxane chemotherapy leads to breast cancer dormancy escape by stromal injury mediated IL-6/MAP2K signaling

R Ganesan, SS Bhasin, U Krishnan, NR Cheemarla… - bioRxiv, 2022 - biorxiv.org
A major cause of cancer recurrence following chemotherapy is cancer dormancy escape.
Taxane-based chemotherapy is standard of care in breast cancer treatment aimed at killing …

播散肿瘤细胞的休眠与存活机制及其在防治实体瘤转移中的作用

阙祖俊, 席志超, 徐宏喜, 田建辉 - 肿瘤防治研究, 2022 - zlfzyj.com
摘要肿瘤转移的防治可显著改善实体瘤患者的生存, 然而目前临床上仍缺乏有效的转移防治药物
, 其根本原因是现有的干预措施和治疗药物都难以实现对转移的精准防治. 由于早期术后患者的 …

Breast cancer recurrence and survival rates in patients who underwent breast‐conserving surgery under non‐mechanically ventilated anesthesia

R Kim, A Kawai, M Wakisaka, M Shimoyama… - Cancer …, 2023 - Wiley Online Library
Background Recurrence after primary treatment is an important obstacle to the curing of
primary breast cancer. Less‐immunosuppressive anesthetic techniques, such as local …

Targeting Dormant Disseminated Tumor Cells and their Permissive Niche by Pro-Resolving Mediators Derived from Resolution-Phase Macrophages.

D Barkan, O Gilon-Zaltsman, K Weidenfeld, H Samara… - 2023 - researchsquare.com
Metastatic breast cancer can recur years after initial treatments and arise from quiescent
disseminated tumor cells (QDTC). To date there are no treatments to target QDTCs …

Dual FGFR-targeting and pH-activable Smart Ruthenium-Peptide Conjugates for targeted therapy of Breast Cancer

JF Machado, M Sá, I Pires, M Silva, F Marques… - 2023 - chemrxiv.org
Dysregulation of Fibroblast Growth Factor Receptors (FGFRs) signaling has been
associated with breast cancer, yet employing FGFR-targeted delivery systems to improve …

Delayed Hepatocellular Carcinoma Recurrence After Liver Transplantation: Comprehensive Clinical Characterization of Case Series

TH Wong, CM Ho, HH Hsu, YM Wu, MC Ho… - Journal of …, 2022 - Taylor & Francis
Purpose Liver transplantation (LT) is the definite curative treatment for hepatocellular
carcinoma (HCC), but recurrence can occur even under stringent criteria.“Delayed” HCC …

Therapeutische Behandlung der minimalen Resterkrankung zur Verhinderung von Spätrezidiven bei Hormonrezeptor-positivem Brustkrebs: Herausforderungen und …

DW Cescon, K Kalinsicy, HA Parsons, KL Smith… - Kompass …, 2022 - karger.com
Obwohl die meisten Brustkrebserkrankungen in einem heilbaren Stadium diagnostiziert
werden, kommt es bei etwa 20% der Frauen im Laufe ihres Lebens zu einem erneuten …

Molecular Mechanisms Underlying Breast Cancer Dormancy

E Chowdhury - 2022 - search.proquest.com
Breast Cancer (BC) has been a highly prevalent cause of morbidity and mortality in women.
The incidence of mortality rate in BC patients increases with age, in which nearly 95% of …

Induction of Oxidative Stress in Myofibroblasts and Dormant Tumor Cells upon Treatment with Pro-Resolving Mediators Secreted by CD11blow Macrophages

H Samara - 2022 - search.proquest.com
The leading cause of death among breast cancer patients is the recurrence of breast cancer
as a metastatic disease after primary tumor resection and adjuvant therapy. Accumulating …

[PDF][PDF] Bone Marrow Endothelial Cells Increase Prostate Cancer Cell Apoptosis in 3D Triculture Model of Reactive Stroma. Biology 2022, 11, 1271

LK Sablatura, TV Tellman, A Kim, MC Farach-Carson - 2022 - academia.edu
The bone marrow tumor microenvironment (BMTE) is a complex network of cells,
extracellular matrix, and sequestered signaling factors that initially act as a hostile …