Delivering the promise of gene therapy with nanomedicines in treating central nervous system diseases
Abstract Central Nervous System (CNS) diseases, such as Alzheimer's diseases (AD),
Parkinson's Diseases (PD), brain tumors, Huntington's disease (HD), and stroke, still remain …
Parkinson's Diseases (PD), brain tumors, Huntington's disease (HD), and stroke, still remain …
Synthetic modified messenger RNA for therapeutic applications
M Gao, Q Zhang, XH Feng, J Liu - Acta biomaterialia, 2021 - Elsevier
Synthetic modified messenger RNA (mRNA) has manifested great potentials for therapeutic
applications such as vaccines and gene therapies, with the recent mRNA vaccines for global …
applications such as vaccines and gene therapies, with the recent mRNA vaccines for global …
Engineered nanomaterials for biomedical applications and their toxicity: a review
Nanotechnology has revolutionized the field of biomedical sciences with smart approaches
of imaging and treatment. This transformation has led to the development of a new field …
of imaging and treatment. This transformation has led to the development of a new field …
Current advances and challenges in COVID-19 vaccine development: from conventional vaccines to next-generation vaccine platforms
The world is grappling with an unprecedented public health crisis COVID-19 pandemic
caused by the novel coronavirus SARS-CoV-2. Due to the high transmission/mortality rates …
caused by the novel coronavirus SARS-CoV-2. Due to the high transmission/mortality rates …
Application of stimuli responsive nanocomposites in drug delivery and theranostics to counter cancer proliferation and drug resistance
Ingenious nanomedical researches have ameliorated outcomes in cancer theranostics.
Though limitations like non specific distribution generating low signal to noise ratio in …
Though limitations like non specific distribution generating low signal to noise ratio in …
The influence of nanoparticulate drug delivery systems in drug therapy
The advancement in medical sciences and perturbing limitations of some conventional drug
delivery systems have triggered extensive research in nanomedicine, and there have been …
delivery systems have triggered extensive research in nanomedicine, and there have been …
The potential of RNA-based therapy for kidney diseases
T Bondue, L van den Heuvel, E Levtchenko… - Pediatric Nephrology, 2023 - Springer
Inherited kidney diseases (IKDs) are a large group of disorders affecting different nephron
segments, many of which progress towards kidney failure due to the absence of curative …
segments, many of which progress towards kidney failure due to the absence of curative …
Nanoparticle-based delivery strategies of multifaceted immunomodulatory RNA for cancer immunotherapy
YJ Yoo, CH Lee, SH Park, YT Lim - Journal of Controlled Release, 2022 - Elsevier
Although cancer immunotherapy has emerged as a novel cancer treatment modality, it still
suffers from low therapeutic efficacy in clinics due to the presence of a low number of …
suffers from low therapeutic efficacy in clinics due to the presence of a low number of …
[HTML][HTML] Biologics, theranostics, and personalized medicine in drug delivery systems
M Puccetti, M Pariano, A Schoubben… - Pharmacological …, 2024 - Elsevier
The progress in human disease treatment can be greatly advanced through the
implementation of nanomedicine. This approach involves targeted and cell-specific therapy …
implementation of nanomedicine. This approach involves targeted and cell-specific therapy …
Scope and challenges of nanoparticle-based mRNA delivery in cancer treatment
Messenger RNA (mRNA) recently emerged as an appealing alternative to treat and prevent
diseases ranging from cancer and Alzheimer's disease to COVID-19 with significant clinical …
diseases ranging from cancer and Alzheimer's disease to COVID-19 with significant clinical …