Owing to the breakthroughs in the prevention and control of the COVID‐19 pandemic,
messenger RNA (mRNA)‐based vaccines have emerged as promising alternatives to …

Biotech drugs, including proteins, hormones, enzymes, DNA/RNA therapies, and cell-based
treatments, are gaining popularity due to their effectiveness. However, effective delivery …

Cross-presentation (XPT) is an adaptation of the cellular process in which dendritic cells
(DCs) present exogenous antigens on major histocompatibility complex (MHC) class I …

Bioactive molecules and their effects have been influenced by their solubility and
administration route. In many therapeutic reagents, the performance of therapeutics is …

As an emerging new class of nucleic acid drugs, messenger RNA (mRNA) has huge
potential in immunotherapy, regenerative medicine, vaccine, and gene editing. Comparing …

The anti-inflammatory cytokine Interleukin-10 (IL-10) is considered an efficient treatment for
corneal inflammation, in spite of its short half-life and poor eye bioavailability. In the present …

The capacity to efficiently deliver the gene-editing enzyme complex to target cells is favored
over other forms of gene delivery as it offers one-time hit-and-run gene editing, thus …

Synthetic mRNA (mRNA) enables transgene expression without the necessity of nuclear
import and the risk of insertional mutagenesis, which makes it an attractive tool for medical …

Synthetic vectors for therapeutic nucleic acid delivery are currently competing significantly
with their viral counter parts due to their reduced immunogenicity, large payload capacity …

Gene therapy uses modern molecular biology methods to repair disease‐causing genes. As
a burgeoning therapeutic, it has been widely applied for cancer therapy. Since 1989, there …