Bradykinesia in Alzheimer's disease and its neurophysiological substrates

M Bologna, A Guerra, D Colella, E Cioffi… - Clinical …, 2020 - Elsevier
Objective Alzheimer's disease is primarily characterized by cognitive decline; recent studies,
however, emphasize the occurrence of motor impairment in this condition. Here, we …

Transcranial magnetic stimulation in Alzheimer's disease: a neurophysiological marker of cortical hyperexcitability

G Pennisi, R Ferri, G Lanza, M Cantone… - Journal of Neural …, 2011 - Springer
Recently, neuropathological studies have shown an important motor cortex involvement in
Alzheimer's disease (AD), even in its early stages, despite the lack of clinically evident motor …

Phase of beta-frequency tACS over primary motor cortex modulates corticospinal excitability

L Schilberg, T Engelen, S Ten Oever, T Schuhmann… - cortex, 2018 - Elsevier
The assessment of corticospinal excitability by means of transcranial magnetic stimulation-
induced motor evoked potentials is an established diagnostic tool in neurophysiology and a …

Functional neurophysiological biomarkers of early-stage Alzheimer's disease: A perspective of network hyperexcitability in disease progression

S Tok, A Ahnaou… - Journal of Alzheimer's …, 2022 - content.iospress.com
Network hyperexcitability (NH) has recently been suggested as a potential
neurophysiological indicator of Alzheimer's disease (AD), as new, more accurate biomarkers …

Alzheimer disease and neuroplasticity

G Koch, D Spampinato - Handbook of Clinical Neurology, 2022 - Elsevier
Alzheimer's disease (AD) is considered the most harmful form of dementia in the elderly
population. At present, there are no effective treatments and this is likely due to the …

[HTML][HTML] Transcranial magnetic stimulation across the lifespan: impact of developmental and degenerative processes

LM Oberman, A Benussi - Biological psychiatry, 2023 - Elsevier
Transcranial magnetic stimulation (TMS) has emerged as a pivotal non-invasive technique
for investigating cortical excitability and plasticity across the lifespan, offering valuable …

Evidence for the specificity of intracortical inhibitory dysfunction in asymptomatic concussed athletes

S Tremblay, L de Beaumont, M Lassonde… - Journal of …, 2011 - liebertpub.com
Sports concussions affect thousands of individuals every year and are a major public health
concern. Still, little is known about the long-term and cumulative effects of concussions on …

Fractional anisotropy changes in Alzheimer's disease depend on the underlying fiber tract architecture: a multiparametric DTI study using joint independent …

SJ Teipel, MJ Grothe, M Filippi… - Journal of …, 2014 - content.iospress.com
Diffusion tensor imaging (DTI) allows the simultaneous measurement of several diffusion
indices that provide complementary information on the substrate of white matter alterations …

Dopamine D2-agonist Rotigotine effects on cortical excitability and central cholinergic transmission in Alzheimer's disease patients

A Martorana, F Di Lorenzo, Z Esposito, TL Giudice… - …, 2013 - Elsevier
Dopamine is a neurotransmitter involved in several brain functions ranging from emotions
control, movement organization to memory formation. It is also involved in the regulation of …

Transcranial magnetic stimulation and brain atrophy: a computer-based human brain model study

T Wagner, U Eden, F Fregni, A Valero-Cabre… - Experimental brain …, 2008 - Springer
This paper is aimed at exploring the effect of cortical brain atrophy on the currents induced
by transcranial magnetic stimulation (TMS). We compared the currents induced by various …