Probiotics as a boon in Food diligence: Emphasizing the therapeutic roles of Probiotic beverages on consumers' health

FM Khan, S Morya, VK Chattu - Journal of Applied …, 2021 - journals.ansfoundation.org
Probiotics are living microorganisms that improve health when eaten or introduced to the
body. They have become an essential aspect of everyone's life now due to these products …

Screening for potent and selective anticlostridial leads among FDA-approved drugs

A AbdelKhalek, H Mohammad, AS Mayhoub… - The Journal of …, 2020 - nature.com
Clostridium difficile is a leading cause of morbidity and mortality particularly in hospital
settings. In addition, treatment is very challenging due to the scarcity of effective therapeutic …

Gut microbiota features associated with Clostridioides difficile colonization in puppies

ASF Berry, BJ Kelly, D Barnhart, DJ Kelly, DP Beiting… - PloS one, 2019 - journals.plos.org
In people, colonization with Clostridioides difficile, the leading cause of antibiotic-associated
diarrhea, has been shown to be associated with distinct gut microbial features, including …

Recent advances in the treatment of C. difficile using biotherapeutic agents

VV Giau, H Lee, SSA An, J Hulme - Infection and Drug Resistance, 2019 - Taylor & Francis
Clostridium difficile (C. difficile) is rapidly becoming one of the most prevalent health care–
associated bacterial infections in the developed world. The emergence of new, more virulent …

Exploring the Multifaceted Therapeutic Potential of Probiotics: A Review of Current Insights and Applications

K Chakravarty, S Gaur, R Kumar, NK Jha… - Probiotics and …, 2024 - Springer
The interplay between human health and the microbiome has gained extensive attention,
with probiotics emerging as pivotal therapeutic agents due to their vast potential in treating …

Computational modeling of the gut microbiota reveals putative metabolic mechanisms of recurrent Clostridioides difficile infection

MA Henson - PLOS Computational Biology, 2021 - journals.plos.org
Approximately 30% of patients who have Clostridioides difficile infection (CDI) will suffer at
least one incident of reinfection. While the underlying causes of CDI recurrence are poorly …

Antiviral activity of the host defense peptide piscidin 1: investigating a membrane-mediated mode of action

T Bepler, MD Barrera, MT Rooney, Y Xiong… - Frontiers in …, 2024 - frontiersin.org
Outbreaks of viral diseases are on the rise, fueling the search for antiviral therapeutics that
act on a broad range of viruses while remaining safe to human host cells. In this research …

Repurposing the veterinary antiprotozoal drug ronidazole for the treatment of Clostridioides difficile infection

A AbdelKhalek, MN Seleem - International journal of antimicrobial agents, 2020 - Elsevier
Clostridioides difficile infection (CDI) is a principal cause of hospital-acquired infections and
fatalities worldwide. The need for new, more potent anticlostridial agents is far from being …

Phenylthiazoles with potent & optimum selectivity toward Clostridium difficile

MMS El-Din, M Hagras, AS Mayhoub - RSC Medicinal Chemistry, 2024 - pubs.rsc.org
Clostridium difficile (C. difficile) is one of the most threatening bacteria globally, causing high
mortality and morbidity in humans and animals, and is considered a public health threat that …

[HTML][HTML] Island biogeography theory and the gut: why taller people tend to harbor more diverse gut microbiomes

KR Sarmiento, A Carr, C Diener, KJ Locey… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Prior work has shown a positive scaling relationship between vertebrate body size and gut
microbiome alpha-diversity. This observation mirrors commonly observed species area …