Infectiousness, reproductive fitness and evolution of drug-resistant Mycobacterium tuberculosis [State of the art]

S Borrell, S Gagneux - The International Journal of …, 2009 - ingentaconnect.com
Mathematical models predict that the future of the multidrug-resistant (MDR) and extensively
drug-resistant (XDR) tuberculosis (TB) epidemic will depend to a large extent on the …

The quiet and controversial: Ural family of Mycobacterium tuberculosis

I Mokrousov - Infection, genetics and evolution, 2012 - Elsevier
The absence of lateral gene exchange is a characteristic feature defining the genome
evolution and clonal population structure of Mycobacterium tuberculosis. Certain of its …

Diagnostic utility of GeneXpert MTB/RIF assay versus conventional methods for diagnosis of pulmonary and extra-pulmonary tuberculosis

AM Elbrolosy, RH El Helbawy, OM Mansour, RA Latif - BMC microbiology, 2021 - Springer
Background Tuberculosis (TB) is one of the major infectious diseases in the developing
countries. The diagnosis of extrapulmonary TB (EPTB) remains problematic and emergence …

[HTML][HTML] Associations between Mycobacterium tuberculosis strains and phenotypes

T Brown, V Nikolayevskyy, P Velji… - Emerging infectious …, 2010 - ncbi.nlm.nih.gov
To inform development of tuberculosis (TB) control strategies, we characterized a total of
2,261 Mycobacterium tuberculosis complex isolates by using multiple phenotypic and …

Performance of the Genotype® MTBDRPlus resistance patternSamara, Russian Federation

V Nikolayevskyy, Y Balabanova, T Simak… - BMC Clinical …, 2009 - Springer
Background Russia is a high tuberculosis (TB) burden country with a high prevalence of
multidrug resistant tuberculosis (MDRTB). Molecular assays for detection of MDRTB on …

Latin-American-Mediterranean lineage of Mycobacterium tuberculosis: Human traces across pathogen's phylogeography

I Mokrousov, A Vyazovaya, T Iwamoto, Y Skiba… - Molecular phylogenetics …, 2016 - Elsevier
Currently, Mycobacterium tuberculosis isolates of Latin-American Mediterranean (LAM)
family may be detected far beyond the geographic areas that coined its name 15 years ago …

[HTML][HTML] Multidrug-and extensively drug-resistant Mycobacterium tuberculosis Beijing clades, Ukraine, 2015

M Merker, E Nikolaevskaya, TA Kohl… - Emerging infectious …, 2020 - ncbi.nlm.nih.gov
Multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) is an
emerging threat to TB control in Ukraine, a country with the third highest XDR TB burden …

DNA repair systems and the pathogenesis of Mycobacterium tuberculosis: varying activities at different stages of infection

AE Gorna, RP Bowater, J Dziadek - Clinical science, 2010 - portlandpress.com
Mycobacteria, including most of all MTB (Mycobacterium tuberculosis), cause pathogenic
infections in humans and, during the infectious process, are exposed to a range of …

Mycobacterium tuberculosis Population in Northwestern Russia: An Update from Russian-EU/Latvian Border Region

I Mokrousov, A Vyazovaya, T Otten, V Zhuravlev… - PloS one, 2012 - journals.plos.org
This study aimed to characterize the population structure of Mycobacterium tuberculosis in
Pskov oblast in northwestern Russia, to view it in the geographical context, to compare drug …

A multifaceted interplay between virulence, drug resistance, and the phylogeographic landscape of Mycobacterium tuberculosis

I Mokrousov, T Vinogradova, M Dogonadze… - Microbiology …, 2023 - Am Soc Microbiol
ABSTRACT Latin-American Mediterranean (LAM) family is one of the most significant and
global genotypes of Mycobacterium tuberculosis. Here, we used the murine model to study …