Spiers Memorial Lecture: Mechanochemistry, tribochemistry, mechanical alloying–retrospect, achievements and challenges

E Boldyreva - Faraday discussions, 2023 - pubs.rsc.org
Spiers Memorial Lecture: Mechanochemistry, tribochemistry, mechanical alloying –
retrospect, achievements and challenges - Faraday Discussions (RSC Publishing) DOI:10.1039/D2FD00149G …

Playing with isostructurality from binary cocrystals to ternary cocrystal solvates of quercetin: tuning colors of pigment

Z Li, J Zhou, K Zhang, Y Zhang, S Wu… - Crystal Growth & …, 2022 - ACS Publications
Tuning the solid-state color properties of pigments tailored for specific applications is
extremely important. With the aim of designing new organic pigment materials, binary and …

Oxaliplatin-flavone pharmaceutical co-crystal-CN111205332A: patent spotlight

R Rathi, R Kushwaha, A Goyal… - Pharmaceutical Patent …, 2022 - Taylor & Francis
Co-crystallization is a technique for modifying physicochemical properties of pharmaceutical
ingredients with an aim to enhance the therapeutic efficacy and subsequent reduction in …

[HTML][HTML] Pirfenidone–flavonoid cocrystals with reduced solubility and dissolution rate

L Meng, D Li, Y Zhu, J Wang, Z Deng, H Zhang - CrystEngComm, 2023 - pubs.rsc.org
Pirfenidone (PFD) is an orally administered medication used for the treatment of idiopathic
pulmonary fibrosis. PFD has excessive solubility and high daily dosage. A sustained-release …

New cocrystals of heterocyclic drugs: structural, antileishmanial, larvicidal and urease inhibition studies

G Murtaza, M Khan, S Farooq… - … Section C: Structural …, 2023 - journals.iucr.org
Many heterocycles have been developed as drugs due to their capacity to interact
productively with biological systems. The present study aimed to synthesize cocrystals of the …

Structural and biopharmaceutical evaluation of newly synthesized norfloxacin co-crystals using crystal engineering approach

M Prashar, V Mehta, P Singh, S Mangal, P Arora… - Journal of Molecular …, 2023 - Elsevier
The study aims to enhance the biopharmaceutical properties of norfloxacin, a water-
insoluble antibacterial antibiotic by synthesizing its co-crystals. Co-crystallization technique …

Enhancing the dissolution and bacteriostatic activity of trimethoprim through salt formation

X Hu, Y Xiao, L Qi, Y Bai, Y Sun, Y Ye, C Xie - CrystEngComm, 2023 - pubs.rsc.org
Trimethoprim (TMP) is a commonly used BCS class II antibiotic, the water solubility of which
needs to be improved to overcome the limitations in oral administration. Herein, we …

Hot Melt Extrusion Technique for Developing Pharmaceutical Co-crystals: A Review

R Rathi, I Singh - Drug Delivery Letters, 2024 - ingentaconnect.com
Background: In the era of pharmaceutical research and development, the most challenging
aspect is to enhance the physicochemical properties of drugs. Hot Melt Extrusion (HME) is a …

[HTML][HTML] Drug release from carrier systems comprising meloxicam crystals formed by impregnation-evaporation

P Zámostný, M Drahozal, O Švehla, S Römerová… - Crystals, 2023 - mdpi.com
The impregnation of poorly water-soluble drug onto the surface of a suitable pharmaceutical
excipient, used as a hydrophilic carrier, can lead to the preparation of systems with improved …

Cristales moleculares de ácidos arilborónicos y trans-1, 2-bis (4-piridil) eteno: influencia de grupos funcionales en la organización tridimensional y fotorreactividad

MB HERNÁNDEZ - 2024 - riaa.uaem.mx
Los experimentos de cocristalización de ácidos organoborónicos con componentes tipo bis-
piridilo, como 4, 4'-bipiridina, 1, 2-bis (4-piridil) etano y 1, 2-bis (4-piridil) eteno, han llevado …