Artificial Intelligence and Neurosurgery: Tracking Antiplatelet Response Patterns for Endovascular Intervention

K Saigal, AB Patel, B Lucke-Wold - Medicina, 2023 - mdpi.com
Platelets play a critical role in blood clotting and the development of arterial blockages.
Antiplatelet therapy is vital for preventing recurring events in conditions like coronary artery …

Biomarkers for antiplatelet therapies in acute ischemic stroke: a clinical review

A Alhazzani, P Venkatachalapathy… - Frontiers in …, 2021 - frontiersin.org
Stroke is one of the world's leading causes of disability and death. Antiplatelet agents are
administered to acute ischemic stroke patients as secondary prevention. Clopidogrel …

Splicing of platelet resident pre-mRNAs upon activation by physiological stimuli results in functionally relevant proteome modifications

G Nassa, G Giurato, G Cimmino, F Rizzo, M Ravo… - Scientific reports, 2018 - nature.com
Platelet activation triggers thrombus formation in physiological and pathological conditions,
such as acute coronary syndromes. Current therapies still fail to prevent thrombotic events in …

Lipoxins, RevD1 and 9, 13 HODE as the most important derivatives after an early incident of ischemic stroke

M Szczuko, D Kotlęga, J Palma, A Zembroń-Łacny… - Scientific reports, 2020 - nature.com
There is limited information available regarding the association of plasma free fatty acids
(FFA) and inflammation mediators with ischemic stroke. At the same time, new treatment …

[HTML][HTML] Platelet testing to guide aspirin dose adjustment in pediatric patients after cardiac surgery

S Emani, D Zurakowski, M Mulone, JA DiNardo… - The Journal of Thoracic …, 2017 - Elsevier
Objectives Thrombosis is associated with increased morbidity and mortality in pediatric
patients undergoing cardiac surgery. Although aspirin commonly is used for …

Bioactive peptides and proteins as alternative antiplatelet drugs

KRR Rengasamy, H Khan, I Ahmad… - Medicinal Research …, 2019 - Wiley Online Library
Antiplatelet drugs reduce the risks associated with atherothrombotic events and show
various applications in diverse cardiovascular diseases including myocardial infarctions …

Pleyotropic antiaggregant effects of an innovative antiarrhythmic of class III SS-68, an indole derivative

BS Kazbekovna, KA Fatihovna… - Research Results in …, 2017 - cyberleninka.ru
Background: A new indole derivative with the lab code-number SS-68 demonstrates a
significant antiarrhythmic (anti-fibrillation) activity associated with the predominant influence …

Anti-platelet therapy resistance–concept, mechanisms and platelet function tests in intensive care facilities

A Mărginean, C Bănescu, A Scridon… - The Journal of Critical …, 2016 - sciendo.com
It is well known that critically ill patients require special attention and additional
consideration during their treatment and management. The multiple systems and organ …

Aspirin & clopidogrel non-responsiveness & its association with genetic polymorphisms in patients with myocardial infarction

CP Pandey, A Misra, MPS Negi… - Indian Journal of …, 2019 - journals.lww.com
Methods: A total of 207 MI patients who were on DAPT, were included. The DAPT non-
responsiveness was determined by light transmittance aggregometry using arachidonic acid …

Platelet receptor Gene (P2Y12, P2Y1) and platelet glycoprotein Gene (GPIIIa) polymorphisms are associated with antiplatelet drug responsiveness and clinical …

X Yi, Q Zhou, C Wang, J Lin, P Liu, C Fu - European journal of clinical …, 2017 - Springer
Purpose Patients with minor ischemic stroke (MIS) are at high risk of recurrent ischemic
stroke (RIS). The aim of this study was to evaluate the effects of platelet receptor gene …