The biofilm matrix: multitasking in a shared space
HC Flemming, ED van Hullebusch, TR Neu… - Nature Reviews …, 2023 - nature.com
The biofilm matrix can be considered to be a shared space for the encased microbial cells,
comprising a wide variety of extracellular polymeric substances (EPS), such as …
comprising a wide variety of extracellular polymeric substances (EPS), such as …
Gradients and consequences of heterogeneity in biofilms
Historically, appreciation for the roles of resource gradients in biology has fluctuated
inversely to the popularity of genetic mechanisms. Nevertheless, in microbiology specifically …
inversely to the popularity of genetic mechanisms. Nevertheless, in microbiology specifically …
Biofilm formation and inhibition mediated by bacterial quorum sensing
Y Wang, Z Bian, Y Wang - Applied Microbiology and Biotechnology, 2022 - Springer
As a complex microbial aggregate, biofilm is a group behavior of bacterial ability to adapt to
the environment. Bacteria produce biofilm substrates that enhance their tolerance to stress …
the environment. Bacteria produce biofilm substrates that enhance their tolerance to stress …
Regulation of Biofilm Exopolysaccharide Biosynthesis and Degradation in Pseudomonas aeruginosa
LZ Ma, D Wang, Y Liu, Z Zhang… - Annual review of …, 2022 - annualreviews.org
Microbial communities enmeshed in a matrix of macromolecules, termed as biofilms, are the
natural setting of bacteria. Exopolysaccharide is a critical matrix component of biofilms …
natural setting of bacteria. Exopolysaccharide is a critical matrix component of biofilms …
The non-attached biofilm aggregate
Biofilms have conventionally been perceived as dense bacterial masses on surfaces,
following the five-step model of development. Initial biofilm research focused on surface …
following the five-step model of development. Initial biofilm research focused on surface …
Extracellular DNA (eDNA). A major ubiquitous element of the bacterial biofilm architecture
D Campoccia, L Montanaro, CR Arciola - International Journal of …, 2021 - mdpi.com
After the first ancient studies on microbial slime (the name by which the biofilm matrix was
initially indicated), multitudes of studies on the morphology, composition and physiology of …
initially indicated), multitudes of studies on the morphology, composition and physiology of …
Polysaccharides' structures and functions in biofilm architecture of antimicrobial-resistant (AMR) pathogens
E Balducci, F Papi, DE Capialbi, L Del Bino - International journal of …, 2023 - mdpi.com
Bacteria and fungi have developed resistance to the existing therapies such as antibiotics
and antifungal drugs, and multiple mechanisms are mediating this resistance. Among these …
and antifungal drugs, and multiple mechanisms are mediating this resistance. Among these …
[HTML][HTML] Mechanisms of antibiotic resistance in Pseudomonas aeruginosa biofilms
M Fernández-Billón, AE Llambías-Cabot… - Biofilm, 2023 - Elsevier
Pseudomonas aeruginosa is a major cause of life-threatening acute infections and life-long
lasting chronic infections. The characteristic biofilm mode of life in P. aeruginosa chronic …
lasting chronic infections. The characteristic biofilm mode of life in P. aeruginosa chronic …
What's in a name? Characteristics of clinical biofilms
In vitro biofilms are communities of microbes with unique features compared to individual
cells. Biofilms are commonly characterized by physical traits like size, adhesion, and a …
cells. Biofilms are commonly characterized by physical traits like size, adhesion, and a …
The Pel polysaccharide is predominantly composed of a dimeric repeat of α-1,4 linked galactosamine and N-acetylgalactosamine
The genetic capacity to synthesize the biofilm matrix exopolysaccharide Pel is widespread
among Gram-negative and Gram-positive bacteria. However, its exact chemical structure …
among Gram-negative and Gram-positive bacteria. However, its exact chemical structure …