[HTML][HTML] Primary Sjögren's syndrome and the eye

O Bjordal, KB Norheim, E Rødahl, R Jonsson… - Survey of …, 2020 - Elsevier
Primary Sjögren syndrome is an autoimmune disease that mainly affects exocrine glands
such as the salivary and lacrimal glands. In addition, systemic involvement is common …

Advances, limitations and future perspectives in the diagnosis and management of dry eye in Sjogren's syndrome

J Vehof, TP Utheim, H Bootsma… - Clinical and …, 2020 - research.rug.nl
Primary Sjogren's syndrome is a complex systemic autoimmune disorder that primarily
affects exocrine glands such as the lacrimal glands. Dry eye disease is one of the most …

Elevated cytokine levels in tears and saliva of patients with primary Sjögren's syndrome correlate with clinical ocular and oral manifestations

X Chen, LA Aqrawi, TP Utheim, B Tashbayev… - Scientific reports, 2019 - nature.com
Investigating cytokines in tear fluid and saliva may offer valuable information for
understanding the pathogenesis of primary Sjögren's syndrome (pSS). Cytokine profiles in …

Meibography: a Japanese perspective

R Arita - Investigative ophthalmology & visual science, 2018 - iovs.arvojournals.org
Meibography allows observation of meibomian glands in an objective and repeatable
manner. Original meibography systems were invasive and not readily adopted by …

The role of meibography in ocular surface diagnostics: A review

F Fineide, R Arita, TP Utheim - The ocular surface, 2021 - Elsevier
The meibomian glands are lipid-secreting glands located in the tarsal plates, whose
secretory products cover the tear film, thereby reducing evaporation as well as ensuring …

Tear metabolomics highlights new potential biomarkers for differentiating between Sjögren's syndrome and other causes of dry eye

G Urbanski, S Assad, F Chabrun, JMC de la Barca… - The Ocular Surface, 2021 - Elsevier
Purpose The lacrimal exocrinopathy of primary Sjögren's syndrome (pSS) is one of the main
causes of severe dry eye syndrome and a burden for patients. Early recognition and …

Dry eye in Sjögren's syndrome–characteristics and therapy

M Caban, W Omulecki… - European Journal of …, 2022 - journals.sagepub.com
Background Sjögren's syndrome is an autoimmune disease, and its important feature is the
lymphocyte infiltration of exocrine glands, including lacrimal glands. It contributes to defects …

Characterization of lipids in saliva, tears and minor salivary glands of Sjögren's syndrome patients using an HPLC/MS-based approach

F Fineide, X Chen, T Bjellaas, V Vitelli… - International Journal of …, 2021 - mdpi.com
The diagnostic work-up of primary Sjögren's syndrome (pSS) includes quantifying saliva and
tear production, evaluation of autoantibodies in serum and histopathological analysis of …

Tear film break-up time and dry eye disease severity in a large Norwegian cohort

M Yazdani, J Fiskådal, X Chen, ØA Utheim… - Journal of Clinical …, 2021 - mdpi.com
This study evaluated to what extent tear film break-up time (TFBUT) could discriminate
pathological scores for other clinical tests and explore the associations between them. Dry …

Patients with non-Sjögren's sicca report poorer general and oral health-related quality of life than patients with Sjögren's syndrome: a cross-sectional study

B Tashbayev, T Garen, Ø Palm, X Chen… - Scientific reports, 2020 - nature.com
Understanding the impact of the disease on quality of life is crucial in patient management.
In this cross-sectional study, general and oral health-related quality of life questionnaires …