Current challenges in the treatment of cardiac fibrosis: Recent insights into the sex‐specific differences of glucose‐lowering therapies on the diabetic heart: IUPHAR …

A Sharma, M De Blasio, R Ritchie - British Journal of …, 2023 - Wiley Online Library
A significant cardiac complication of diabetes is cardiomyopathy, a form of ventricular
dysfunction that develops independently of coronary artery disease, hypertension and …

Distinct pathophysiological pathways in women and men with heart failure

A Ravera, BT Santema, RA de Boer… - European journal of …, 2022 - Wiley Online Library
Aims Clinical differences between women and men have been described in heart failure
(HF). However, less is known about the underlying pathophysiological mechanisms. In this …

Alamandine alleviated heart failure and fibrosis in myocardial infarction mice

K Zhao, T Xu, Y Mao, X Wu, D Hua, Y Sheng, P Li - Biology Direct, 2022 - Springer
Alamandine (Ala) is the newest identified peptide of the renin-angiotensin system and has
protective effect on myocyte hypertrophy. However, it is still unclear whether Ala can …

New perspectives on sex Steroid and Mineralocorticoid receptor signaling in cardiac ischemic injury

LA Bienvenu, JR Bell, KL Weeks… - Frontiers in …, 2022 - frontiersin.org
The global burden of ischemic heart disease is burgeoning for both men and women.
Although advances have been made, the need for new sex-specific therapies targeting key …

Chemical Synthesis, Safety and Efficacy of Antihypertensive Candidate Drug 221s (2, 9)

B Qin, L Yu, R Wang, Y Tang, Y Chen, N Wang… - Molecules, 2023 - mdpi.com
Hypertension is the main risk factor of cardiovascular and cerebrovascular diseases. In this
paper, a novel compound known as 221s (2, 9), which includes tanshinol, borneol and a …

Sex differences in therapies for heart failure

D Miličić, M Bergami… - Current Pharmaceutical …, 2022 - ingentaconnect.com
Heart failure (HF) is a common cause of morbimortality with different etiopathogenesis and
prognosis between men and women. This review provides a brief overview of gender-based …

[HTML][HTML] Sex differences of angiotensin-converting enzyme inhibitors in blood pressure lowering and cardiac remodeling: a systematic review and meta-analysis

SAJS Laven, DAM Meijs, Z Mohseni-Alsalhi… - Medical Research …, 2023 - esmed.org
Objectives: Hypertension is the leading risk factor for cardiovascular disease. While
treatment of high blood pressure is essential in cardiovascular disease prevention or …

Deciphering Sex-Specific Pathologies in CAVD Through Disease-Inspired Engineered Valve Models

LF Rios - 2024 - search.proquest.com
Abstract Calcific Aortic Valve Disease (CAVD) is one of the most common valvular ailments,
affecting over 10 million Americans each year over the age of 65. Despite its similarities with …

[PDF][PDF] Insuficiencia cardíaca en la mujer

MJ Estebanez - 2022 - insuficienciacardiaca.org
La prevalencia de la insuficiencia cardíaca (IC) está aumentando incesantemente y es la
principal causa de ingresos hospitalarios en la población adulta, afectando tanto a hombres …

[PDF][PDF] Sex Differences: Potential Impact in Vascular Physiopathology or Ischemic Heart Disease

JG Kingma Jr - Cardiol Vasc Res, 2022 - scivisionpub.com
Pathophysiological mechanisms for development and progression of ischemic heart
disease, which is essentially an age-related condition, may differ between men and women …