[HTML][HTML] Levodopa-induced dyskinesia in Parkinson's disease: pathogenesis and emerging treatment strategies
The most commonly used treatment for Parkinson's disease (PD) is levodopa, prescribed in
conjunction with carbidopa. Virtually all patients with PD undergo dopamine replacement …
conjunction with carbidopa. Virtually all patients with PD undergo dopamine replacement …
Intranasal nanotherapeutics for brain targeting and clinical studies in Parkinson's disease
Parkinson's disease (PD) is the second leading neurodegenerative disease globally,
impacting the quality of life of millions of people. It is estimated that the treatment cost of PD …
impacting the quality of life of millions of people. It is estimated that the treatment cost of PD …
Nose-to-brain delivery of rotigotine redispersible nanosuspension: In vitro and in vivo characterization
Rotigotine (RTG) is an anti-Parkinson's drug approved by the USFDA to treat motor and non-
motor symptoms of both early and advanced stages of the disease. However, issues like …
motor symptoms of both early and advanced stages of the disease. However, issues like …
Targeting G protein-coupled receptors in the treatment of Parkinson's disease
J Jones-Tabah - Journal of Molecular Biology, 2023 - Elsevier
Parkinson's disease (PD) is a progressive neurodegenerative disease characterized in part
by the deterioration of dopaminergic neurons which leads to motor impairment. Although …
by the deterioration of dopaminergic neurons which leads to motor impairment. Although …
Snake venom nerve growth factor-inspired designing of novel peptide therapeutics for the prevention of paraquat-induced apoptosis, neurodegeneration, and …
Neurodegenerative disorders (ND), associated with the progressive loss of neurons,
oxidative stress-mediated production of reactive oxygen species (ROS), and mitochondrial …
oxidative stress-mediated production of reactive oxygen species (ROS), and mitochondrial …
Self-assembled ruthenium decorated electrochemical platform for sensitive and selective determination of amisulpride in presence of co-administered drugs using …
A wholly new electroanalytical protocol for the sensitive determination of Amisulpride (AMS)
has been developed. AMS is an antipsychotic and antiemetic medicine that is prescribed at …
has been developed. AMS is an antipsychotic and antiemetic medicine that is prescribed at …
[HTML][HTML] The effect and safety of ropinirole in the treatment of Parkinson disease: a systematic review and meta-analysis
J Zhu, M Chen - Medicine, 2021 - journals.lww.com
Background: It is necessary to conduct a meta-analysis of the clinical randomized controlled
trials (RCTs) on ropinirole in the treatment of Parkinson disease (PD), to explore the effects …
trials (RCTs) on ropinirole in the treatment of Parkinson disease (PD), to explore the effects …
[HTML][HTML] Identification of potential Parkinson's disease drugs based on multi-source data fusion and convolutional neural network
J Liu, D Peng, J Li, Z Dai, X Zou, Z Li - Molecules, 2022 - mdpi.com
Parkinson's disease (PD) is a serious neurodegenerative disease. Most of the current
treatment can only alleviate symptoms, but not stop the progress of the disease. Therefore, it …
treatment can only alleviate symptoms, but not stop the progress of the disease. Therefore, it …
Prevalence and correlates of psychiatric comorbidity and multimorbidity in Parkinson's disease and atypical parkinsonian syndromes
Purpose Psychiatric comorbidity in Parkinson's disease (PD) and atypical parkinsonian
syndromes (APS) has been consistently associated with poor outcomes. However, the co …
syndromes (APS) has been consistently associated with poor outcomes. However, the co …
Future Directions for Developing Non-dopaminergic Strategies for the Treatment of Parkinson's Disease
DJ Wamelen, V Leta, K Chaudhuri… - Current …, 2024 - ingentaconnect.com
The symptomatic treatment of Parkinson's disease (PD) has been dominated by the use of
dopaminergic medication, but significant unmet need remains, much of which is related to …
dopaminergic medication, but significant unmet need remains, much of which is related to …