Structural and biochemical features of human serum albumin essential for eukaryotic cell culture

V Mishra, RJ Heath - International journal of molecular sciences, 2021 - mdpi.com
Serum albumin physically interacts with fatty acids, small molecules, metal ions, and several
other proteins. Binding with a plethora of bioactive substances makes it a critical transport …

Application of stem cell therapy for infertility

S Saha, P Roy, C Corbitt, SS Kakar - Cells, 2021 - mdpi.com
Infertility creates an immense impact on the psychosocial wellbeing of affected couples,
leading to poor quality of life. Infertility is now considered to be a global health issue …

The use of stem cell-derived organoids in disease modeling: an update

J Azar, HF Bahmad, D Daher, MM Moubarak… - International Journal of …, 2021 - mdpi.com
Organoids represent one of the most important advancements in the field of stem cells
during the past decade. They are three-dimensional in vitro culturing models that originate …

Cell therapy in female infertility-related diseases: Emphasis on recurrent miscarriage and repeated implantation failure

R Pourakbari, H Ahmadi, M Yousefi, L Aghebati-Maleki - Life sciences, 2020 - Elsevier
About 17% of couples suffer from infertility conditions, worldwide. The most common
reasons for female infertility are ovulation disorders, fallopian-related disorders, RM, RIF …

[HTML][HTML] Animal-derived products in science and current alternatives

AC Duarte, EC Costa, HAL Filipe, SM Saraiva… - Biomaterials …, 2023 - Elsevier
More than fifty years after the 3Rs definition and despite the continuous implementation of
regulatory measures, animals continue to be widely used in basic research. Their use …

Distinct metabolic states can support self-renewal and lipogenesis in human pluripotent stem cells under different culture conditions

H Zhang, MG Badur, AS Divakaruni, SJ Parker, C Jäger… - Cell reports, 2016 - cell.com
Recent studies have suggested that human pluripotent stem cells (hPSCs) depend primarily
on glycolysis and only increase oxidative metabolism during differentiation. Here, we …

The induced pluripotent stem cells in articular cartilage regeneration and disease modelling: are we ready for their clinical use?

MS Lach, MA Rosochowicz, M Richter, I Jagiełło… - Cells, 2022 - mdpi.com
The development of induced pluripotent stem cells has brought unlimited possibilities to the
field of regenerative medicine. This could be ideal for treating osteoarthritis and other …

Human pluripotent stem cells in neurodegenerative diseases: potentials, advances and limitations

TA Kolagar, M Farzaneh, N Nikkar… - Current stem cell …, 2020 - ingentaconnect.com
Neurodegenerative diseases are progressive and uncontrolled gradual loss of motor
neurons function or death of neuron cells in the central nervous system (CNS) and the …

Pluripotent stem cells in developmental toxicity testing: a review of methodological advances

AL Luz, EJ Tokar - Toxicological Sciences, 2018 - academic.oup.com
Millions of children are born each year with a birth defect. Many of these defects are caused
by environmental factors, although the underlying etiology is often unknown. In vivo …

Stem cells as a resource for treatment of infertility-related diseases

J Wang, C Liu, M Fujino, G Tong… - Current molecular …, 2019 - ingentaconnect.com
Worldwide, infertility affects 8-12% of couples of reproductive age and has become a
common problem. There are many ways to treat infertility, including medication, intrauterine …