Bacillus Calmette-Guérin (BCG) therapy for bladder cancer: an update

S Guallar-Garrido, E Julián - ImmunoTargets and therapy, 2020 - Taylor & Francis
Physicians treating patients affected by nonmuscle-invasive bladder cancer (NMIBC) have
been in shock during the last six years since manufacturing restrictions on the production of …

[HTML][HTML] Anti-oncogenic effects of dutasteride, a dual 5-alpha reductase inhibitor and a drug for benign prostate hyperplasia, in bladder cancer

J Seok, HJ Kwak, Y Kwak, M Lee, KS Park… - Journal of Translational …, 2023 - Springer
Background The incidence of bladder cancer (BCa) is approximately four times higher in
men than in women. To develop effective BCa treatments, there is an urgent need to …

Chapter 7: Extra-pulmonary tuberculosis

L Barss, WJA Connors, D Fisher - Canadian Journal of Respiratory …, 2022 - Taylor & Francis
5. We conditionally recommend initial adjunctive corticosteroid treatment in all human
immunodeficiency virus (HIV)-negative patients with TB pericarditis. Routine use of …

Quantitative transcriptomic and proteomic analysis reveals corosolic acid inhibiting bladder cancer via suppressing cell cycle and inducing mitophagy in vitro and in …

A Cui, X Li, X Ma, Z Song, X Wang, C Wang… - Toxicology and Applied …, 2023 - Elsevier
Corosolic acid (CA) is a plant-derived terpenoid compound with many health benefits.
However, the anti-tumor effects of CA in bladder cancer remain unexplored. Here, we found …

Systemic BCGosis following intra-renal instillation of BCG: a case report

J Schembri Higgans, K Pace… - Journal of Surgical …, 2021 - academic.oup.com
Abstract Bacillus Calmette-Guerin (BCG) immunotherapy is a mainstay of adjunctive therapy
for non-muscle-invasive bladder cancer. The instillation of BCG in the upper urinary tract …

[PDF][PDF] Transcriptome and proteome analysis reveals corosolic acid inhibiting bladder cancer via targeting cell cycle and inducing mitophagy in vitro and in vivo

A Cui, X Li, X Ma, X Wang, C Liu, Z Song, F Pan, Y Xia… - 2021 - scholar.archive.org
Background Existing chemotherapy and radiotherapy methods have drawbacks such as
high toxicity, high side effects, poor e cacy, and chemoresistance. Therefore, there is an …

Systemic infection following intravesical therapy with BCG

AA Oliveira, J Morais, J Ribeiro… - BMJ Case Reports …, 2021 - casereports.bmj.com
Immunotherapy with BCG is an effective and widely used treatment for non-muscle-invasive
bladder cancer. BCG sepsis is a rare but life-threatening and frequently not a straightforward …

BCG and Autoimmunity

E Dogan, OF Deniz, OF Dogru, N Mahroum - Infection and Autoimmunity, 2024 - Elsevier
The nonspecific effects of BCG are not fully understood nevertheless,“trained immunity” and
“heterologous lymphocyte responses” have been suggested. For instance, intravesical BCG …

[HTML][HTML] A solitary pulmonary nodule caused by Mycobacterium tuberculosis var. BCG after intravesical BCG treatment: a case report

M Itai, M Yamasue, S Takikawa, K Komiya… - BMC Pulmonary …, 2021 - Springer
Background Intravesical instillation of bacillus Calmette–Guérin (BCG) as a treatment for
superficial bladder cancer rarely causes pulmonary complications. While published cases …

[HTML][HTML] Difficulties in diagnosing and treating disseminated Bacillus Calmette-Guerin (BCG) infection after intravesical BCG therapy in a patient with liver cirrhosis: a …

C Vallilas, M Zachou, P Dolkiras… - The American Journal …, 2021 - ncbi.nlm.nih.gov
Objective: Rare coexistence of disease or pathology Background: Bladder cancer (BC) is the
second most common cancer involving the urinary system. In non-muscle-invading BC …