Binding of combined irinotecan and epicatechin to a pH-responsive DNA tetrahedron for controlled release and enhanced cytotoxicity

L Wang, Y Wu, T Weng, X Li, X Zhang, Y Zhang… - Journal of Molecular …, 2023 - Elsevier
Abstract pH-Responsive aptamer-linked DNA nanostructures can actively target cancer cells
to release drugs in the cells' acidic environment. Tea polyphenols can be used as cancer …

Insights on the interaction mechanism of sesquiterpene coumarin (7-geranyloxycoumarin) to double-strand DNA by multispectral techniques and molecular docking

B Dehghan, G Dehghan, M Shaghaghi… - Journal of Molecular …, 2024 - Elsevier
In this study, various spectroscopic methods, including UV-Vis spectrophotometry,
fluorescence (competitive and non-competitive studies and binding thermodynamic …